H MATTER
Overview
Explore the profile of H MATTER including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
168
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Recent Articles
1.
Gregory V, Bennett M, Thomas Y, Kaiser L, Wunderli W, MATTER H, et al.
Arch Virol
. 2003 Mar;
148(4):793-802.
PMID: 12664301
The isolation of A/Switzerland/8808/2002 provides further evidence of sporadic human infection by contemporary swine influenza A H1N1 viruses, antigenically and genetically distinct from H1N1 viruses circulating in the human population....
2.
Kotsonis P, Frohlich L, Raman C, Li H, Berg M, Gerwig R, et al.
J Biol Chem
. 2001 Oct;
276(52):49133-41.
PMID: 11590164
Pathological nitric oxide (NO) generation in sepsis, inflammation, and stroke may be therapeutically controlled by inhibiting NO synthases (NOS). Here we targeted the (6R)-5,6,7,8-tetrahydro-l-biopterin (H(4)Bip)-binding site of NOS, which, upon...
3.
MATTER H, Baringhaus K, Naumann T, Klabunde T, Pirard B
Comb Chem High Throughput Screen
. 2001 Sep;
4(6):453-75.
PMID: 11562252
During the practice of combinatorial chemistry, it has been realized that molecular diversity is not the only essential feature in a synthetically feasible library. In addition, it is of utmost...
4.
Heinelt U, Herok S, MATTER H, Wildgoose P
Bioorg Med Chem Lett
. 2001 Feb;
11(2):227-30.
PMID: 11206465
Starting from the achiral and potent factor Xa inhibitor 1, a new and flexible solid-phase optimisation strategy is described to reduce its cationic character. By replacing one positively charged side...
5.
Baringhaus K, MATTER H, Stengelin S, Kramer W
J Lipid Res
. 1999 Dec;
40(12):2158-68.
PMID: 10588941
To design a reliable 3D QSAR model of the intestinal Na(+)/bile acid cotransporter, we have used a training set of 17 inhibitors of the rabbit ileal Na(+)/bile acid cotransporter. The...
6.
MATTER H, Schwab W
J Med Chem
. 1999 Dec;
42(22):4506-23.
PMID: 10579815
A novel strategy to understand affinity and selectivity for enzyme inhibitors using information from ligands and target protein 3D structures is described. It was applied to 2-arylsulfonyl-1,2,3, 4-tetrahydro-isoquinoline-3-carboxylates and -hydroxamates...
7.
Frohlich L, Kotsonis P, Traub H, Hofmann H, Strobel H, MATTER H, et al.
J Med Chem
. 1999 Oct;
42(20):4108-21.
PMID: 10514281
The family of nitric oxide synthases (NOS) catalyzes the conversion of L-arginine to L-citrulline and nitric oxide (NO), an important cellular messenger molecule which has been implicated in the pathophysiology...
8.
MATTER H, Schwab W, Barbier D, Billen G, Haase B, Neises B, et al.
J Med Chem
. 1999 Jun;
42(11):1908-20.
PMID: 10354399
A set of 90 novel 2-(arylsulfonyl)-1,2,3, 4-tetrahydroisoquinoline-3-carboxylates and -hydroxamates as inhibitors of the matrix metalloproteinase human neutrophil collagenase (MMP-8) was designed, synthesized, and investigated by 3D-QSAR techniques (CoMFA, CoMSIA) and...
9.
MATTER H
J Pept Res
. 1998 Dec;
52(4):305-14.
PMID: 9832309
Important molecular descriptors used for establishing quantitative structure-activity relationships are investigated to classify similar versus dissimilar peptides. When searching new lead structures, synthesizing and testing compounds which are too similar...
10.
Zimmermann H, Pfiffner D, Bourquin C, MATTER H
Rev Med Suisse Romande
. 1998 Jun;
118(4):301-8.
PMID: 9623280
No abstract available.