H M Hoffmann
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Explore the profile of H M Hoffmann including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
228
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Recent Articles
1.
Hoffmann H, Dunkel R, Mentzel M, Reuter H, Stark C
Chemistry
. 2002 Jan;
7(22):4771-89.
PMID: 11763446
The de novo synthesis of a full set of hydroxymethyl C-glycosides from only two precursors is described. The seven-carbon target molecules contain five stereocentres and bridge the stereochemical gap between...
2.
Vakalopoulos A, Hoffmann H
Org Lett
. 2001 Jul;
3(14):2185-8.
PMID: 11440575
[reaction: see text] Double deprotection of dithiane aldol equivalents is feasible under mild conditions with ZnBr(2) and suitably placed MEM, BOM, and SEM groups which function as protecting, activating, and...
3.
Vakalopoulos A, Hoffmann H
Org Lett
. 2001 Jun;
3(2):177-80.
PMID: 11430028
[figure: see text] A new rearrangement of functionalized methoxy glycosides and a regioselective as well as stereoselective intramolecular Michael addition giving delta-valerolactones and C-glycosides are described. Applications to the synthesis...
4.
Vakalopoulos A, Lampe T, Hoffmann H
Org Lett
. 2001 Mar;
3(6):929-32.
PMID: 11263918
Starting from 8-oxabicyclo[3.2.1]oct-6-en-3-one and racemic 2,2-dimethyl-8-oxabicyclo[3.2.1]oct-6-en-3-one, the C1-C16 segment of the bryostatins has been synthesized in 30 steps and 9% overall yield (17 steps longest linear sequence). Fragment coupling by...
5.
Skovgaard A, Hoffmann H, Moszkowicz M, Bjornholm K
Ugeskr Laeger
. 2001 Mar;
163(8):1112-5.
PMID: 11242673
Introduction: A descriptive epidemiological study of children aged 0-36 months. Methods: Diagnoses reported from the child psychiatric departments to The National Psychiatric Register were collected from a three-year period 1996,...
6.
Roper S, Frackenpohl J, Schrake O, Wartchow R, Hoffmann H
Org Lett
. 2000 Jul;
2(12):1661-4.
PMID: 10880195
[reaction: see text] A new class of doubly functionalized and enantiomerically pure 1-azabicyclo[3.2.2]nonanes derived from quincorine and quincoridine is described. 2,5-Disubstituted quinuclidines with a C9-mesyloxy group were easily transformed into...
7.
Frackenpohl J, Hoffmann H
J Org Chem
. 2000 Jun;
65(13):3982-96.
PMID: 10866617
The pseudoenantiomeric title compounds have been prepared from quincorine (QCI) and quincoridine (QCD), respectively, in enantiopure form following an efficient six-step pathway. Nucleophilic attack at the carbonyl group proceeds preferentially...
8.
Ryoo H, Hoffmann H, Beumer T, Frenkel B, Towler D, Stein G, et al.
Mol Endocrinol
. 1997 Nov;
11(11):1681-94.
PMID: 9328350
Two homeotic genes, Dlx and Msx, appear to regulate development of mineralized tissues, including bone, cartilage, and tooth. Expression of Msx-1 and Msx-2 has been studied during development of the...
9.
Hoffmann H, Beumer T, Rahman S, McCabe L, Banerjee C, Aslam F, et al.
J Cell Biochem
. 1996 May;
61(2):310-24.
PMID: 9173094
Bone-specific expression of the osteocalcin gene is transcriptionally controlled. Deletion analysis of osteocalcin promoter sequences by transient transfection of osseous (ROS 17/2.8) and nonosseous (R2 fibroblast) cells revealed that the...
10.
Wang Z, Hoffmann H, Grabowski P
RNA
. 1995 Mar;
1(1):21-35.
PMID: 7489484
A functional analysis of exon replacement mutations was performed in parallel with RNA-protein binding assays to gain insight into the role of the exon in alternative and simple splicing events....