H K Bojes
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Explore the profile of H K Bojes including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
279
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Recent Articles
11.
Bojes H, Sausen P, Cattley R, Keller B, Thurman R
Toxicol Appl Pharmacol
. 1996 Apr;
137(2):202-9.
PMID: 8661345
WY-14,643, a lipid-lowering drug, increases basal rates of oxygen uptake in perfused livers. Because peroxisomes consume oxygen for H2O2 production and are induced by WY-14,643 treatment, it is possible that...
12.
Bojes H, Thurman R
Cancer Res
. 1996 Jan;
56(1):1-4.
PMID: 8548746
The mechanism by which peroxisome proliferators increase cell replication and cause liver tumors in rodents remains unknown. When activated, Kupffer cells, the resident hepatic macrophages, release a variety of mitogenic...
13.
Wan Y, Morimoto M, Thurman R, Bojes H, French S
Life Sci
. 1995 Jan;
56(5):307-17.
PMID: 7837930
Peroxisome proliferator-activated receptor (PPAR) and retinoid x receptor (RXR) play important roles in fatty acid metabolism. The present study examined the regulation of retinoic acid receptor (RAR alpha, beta, and...
14.
Adachi Y, Bradford B, Gao W, Bojes H, Thurman R
Hepatology
. 1994 Aug;
20(2):453-60.
PMID: 8045507
It is well recognized that consumption of alcohol leads to liver disease in a dose-dependent manner; however, the exact mechanisms remain unclear. Hypoxia subsequent to a hypermetabolic state may be...
15.
Bojes H, Thurman R
Toxicol Appl Pharmacol
. 1994 Jun;
126(2):233-9.
PMID: 8209376
The mechanism by which hypolipidemic drugs and industrial plasticizers cause hepatic tumors in rodents remains unknown. It is known, however, that protein kinase C is elevated during hepatic cell turnover,...
16.
Keller B, Bradford B, Marsman D, Cattley R, Popp J, Bojes H, et al.
Toxicol Appl Pharmacol
. 1993 Mar;
119(1):52-8.
PMID: 8470123
Wy-14,643 is a potent nongenotoxic hepatic carcinogen and peroxisome proliferator in rodents; however, the mechanism by which it causes tumors remains unknown. In previous work it was demonstrated that Wy-14,643...
17.
Bojes H, Keller B, Thurman R
Toxicol Lett
. 1992 Sep;
62(2-3):317-22.
PMID: 1412517
The mechanism by which hypolipidemic drugs and industrial plasticizers cause hepatic tumors in rodents remains unknown. Protein kinase C is elevated during hepatic cell turnover, and sustained cellular replication has...