R G Thurman
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Explore the profile of R G Thurman including associated specialties, affiliations and a list of published articles.
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420
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5682
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Recent Articles
1.
Reinke L, Kauffman F, Thurman R
Biochem Pharmacol
. 2010 Mar;
29(5):813-9.
PMID: 20227961
Xylitol and sorbitol, two sugar alcohols which readily enter into pathways of hepatic carbohydrate metabolism, stimulated p-nitroanisole O-demethylation in perfused livers from fasted, but not fed, phenobarbital-treated rats. The increase...
2.
Kauffman F, Evans R, Reinke L, Belinsky S, Ballow C, Thurman R
Biochem Pharmacol
. 2010 Mar;
29(5):697-700.
PMID: 20227942
Treatment of adult rats with 3-methylcholanthrene over a 3-day period produced significant decreases in hepatic ATP concentrations and elevated the activities of 6-phosphogluconate dehydrogenase and malic enzyme. The decline in...
3.
[Preparing the donor with glycine improves survival after liver transplantation in the animal model]
Schemmer P, Bunzendahl H, Thurman R
Langenbecks Arch Chir Suppl Kongressbd
. 2003 Oct;
115(Suppl I):589-93.
PMID: 14518323
The etiology of primary graft non-function has been linked to storage and reperfusion injury. Recently, graft manipulation during harvest was shown to aggravate reperfusion injury in livers effecting outcome after...
4.
v Frankenberg M, Forman D, Frey W, Bunzendahl H, Thurman R
Langenbecks Arch Chir Suppl Kongressbd
. 2003 Oct;
115(Suppl I):575-9.
PMID: 14518320
The analysis of amino acids in perfusion effluents in experimental liver transplantation is a valid parameter of organ viability at organ harvest. Depletion of Kupffer cells with gadolinium chloride (GdCl3)...
5.
Israel Y, Crews F, Thurman R, Tu G, Garver E, Ponnappa B, et al.
Alcohol Clin Exp Res
. 2002 May;
26(4):582-5.
PMID: 11981136
This article represents the proceedings of a symposium at the 2001 annual meeting of the Research Society on Alcoholism in Montreal, Canada. Drs. Yedy Israel and Fulton Crews were organizers...
6.
Yamashina S, Konno A, Wheeler M, Rusyn I, Rusyn E, Cox A, et al.
Nutr Cancer
. 2002 Apr;
40(2):197-204.
PMID: 11962256
Glycine inhibited growth of B16 melanoma tumors in vivo most likely because of the inhibition of angiogenesis. Here, the hypothesis that the anticancer effect of glycine in vivo is due...
7.
Zhong Z, Froh M, Wheeler M, Smutney O, Lehmann T, Thurman R
Gene Ther
. 2002 Feb;
9(3):183-91.
PMID: 11859421
Hydrophobic bile acids lead to generation of oxygen free radicals in mitochondria. Accordingly, this study investigated if gene delivery of superoxide dismutase (SOD) would reduce hepatic injury caused by experimental...
8.
Wheeler M, Katuna M, Smutney O, Froh M, Dikalova A, Mason R, et al.
Hum Gene Ther
. 2002 Jan;
12(18):2167-77.
PMID: 11779401
The purpose of this study was to investigate the effectiveness of superoxide dismutase (SOD) overexpression in an acute model of hepatic oxidative stress. Oxidative stress was established using a warm...
9.
Wheeler M, Kono H, Yin M, Nakagami M, Uesugi T, Arteel G, et al.
Free Radic Biol Med
. 2001 Dec;
31(12):1544-9.
PMID: 11744328
Considerable evidence for a role of Kupffer cells in alcoholic liver disease has accumulated and they have recently been shown to be a predominant source of free radicals. Several approaches...
10.
Uesugi T, Froh M, Arteel G, Bradford B, Gabele E, Wheeler M, et al.
Hepatology
. 2001 Dec;
34(6):1149-57.
PMID: 11732004
Chronic alcohol administration increases gut-derived endotoxin in the portal blood, which activates Kupffer cells through nuclear factor kappaB (NF-kappaB) to produce toxic mediators such as proinflammatory cytokines, leading to liver...