Drug Metabolism Reviews
Overview
Drug Metabolism Reviews is a scholarly journal that provides comprehensive and up-to-date reviews on the metabolism, pharmacokinetics, and disposition of drugs. It covers various aspects of drug metabolism, including enzymology, drug-drug interactions, genetic polymorphisms, and toxicology. This journal serves as a valuable resource for researchers, pharmacologists, and clinicians interested in understanding the complex processes involved in drug metabolism.
Details
Details
Abbr.
Drug Metab Rev
Publisher
Informa Healthcare
Start
1972
End
Continuing
Frequency
Quarterly
p-ISSN
0360-2532
e-ISSN
1097-9883
Country
United Kingdom
Language
English
Specialty
Pharmacology
Metrics
Metrics
h-index / Ranks: 2718
108
SJR / Ranks: 4681
870
CiteScore / Ranks: 1055
11.50
JIF / Ranks: 1162
5.9
Recent Articles
1.
He C, Mao Y, Wan H
Drug Metab Rev
. 2025 Feb;
:1-43.
PMID: 40008940
Idiosyncratic drug-induced liver injury (DILI) is a leading cause of drug attrition and/or withdrawal. The formation of reactive metabolites is widely accepted as a key factor contributing to idiosyncratic DILI....
2.
Costa Alegre M, Barbosa D, Dinis-Oliveira R
Drug Metab Rev
. 2025 Feb;
:1-32.
PMID: 39945551
Trazodone, nefazodone, and etoperidone are classified as atypical antidepressants belonging to the phenylpiperazine class. These antidepressants are primarily metabolized by CYP3A4 into -chlorophenylpiperazine (CPP), which was initially employed in veterinary...
3.
Liu J, Zhang D
Drug Metab Rev
. 2025 Feb;
57(1):51-66.
PMID: 39906921
Cytochrome P450 (CYPs) enzymes are essential for the metabolism of numerous drug compounds and are capable of catalyzing many types of biotransformation reactions. One of the more unusual reactions catalyzed...
4.
Zimmer A, Collier A
Drug Metab Rev
. 2025 Feb;
:1-24.
PMID: 39898873
The use of - physiologically based pharmacokinetic (IVIVE-PBPK) modeling approaches assists for prediction of first-in animal or human trials. These approaches are underpinned by the scaling factors: microsomal protein per...
5.
Li K, Lauschke V, Zhou Y
Drug Metab Rev
. 2025 Jan;
57(1):67-90.
PMID: 39811883
Idiosyncratic drug reactions (IDRs) pose severe threats to patient health. Unlike conventionally dose-dependent side effects, they are unpredictable and more frequently manifest as life-threatening conditions, such as severe cutaneous adverse...
6.
Beigoli S, Kiani S, Asgharzadeh F, Memarzia A, Boskabady M
Drug Metab Rev
. 2024 Dec;
57(1):26-50.
PMID: 39726246
Several studies indicate various pharmacological and therapeutic effects of peroxisome proliferator-activated receptors (PPARs) in different disorders. The current review describes the influences of PPARs on respiratory, allergic, and immunologic diseases....
7.
Wang T, Chen X, Gao Q, Huang C, Wang K, Qiu F
Drug Metab Rev
. 2024 Dec;
57(1):9-25.
PMID: 39692050
(AR) is one of the most widely used herbs in Asia and has a wide range of biological activities. These activities are attributed to its various compounds like flavonoids, saponins,...
8.
Patil V, Seth B, Chaudhari H
Drug Metab Rev
. 2024 Dec;
57(1):1-8.
PMID: 39636221
Alogliptin is an oral hypoglycemic agent selective inhibitor of the dipeptidyl peptidase-4 (DPP-4) enzyme. Inhibition of DPP-4 increases the levels of the incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent...
9.
Zou X, Xu H, Qian W
Drug Metab Rev
. 2024 Oct;
56(4):399-412.
PMID: 39376171
Osteoarthritis (OA) is a chronic degenerative disease caused by various factors such as aging, obesity, trauma, and genetics. It is a challenging condition faced by orthopedic doctors in clinical practice...
10.
Wu Z, Shangguan D, Huang Q, Wang Y
Drug Metab Rev
. 2024 Oct;
56(4):349-358.
PMID: 39350738
root (PMR, Polygoni Multiflori Radix) is an herbal medicine widely used in East Asia, particularly China. However, the potential hepatotoxicity has hindered its rational and safe application of PMR in...