H J Deaizpurua
Overview
Explore the profile of H J Deaizpurua including associated specialties, affiliations and a list of published articles.
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15
Citations
233
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Recent Articles
1.
Naselli G, Deaizpurua H, Thomas H, Johnston A, Kay T
Int J Exp Diabetes Res
. 2001 Jul;
1(4):239-48.
PMID: 11467415
Cytokine receptors from the IL-6 receptor family are comprised of ligand specific alpha chains and a common signalling chain, gp-130, which is also required for high affinity binding. A cDNA...
2.
Johnston A, Naselli G, Gonez L, Martin R, Harrison L, Deaizpurua H
Oncogene
. 2000 Sep;
19(37):4290-7.
PMID: 10980603
We have cloned a member of the STE20/SPS1 protein kinase family from a transformed rat pancreatic beta cell line. SPAK (STE20/SPS1-related, proline alanine-rich kinase) belongs to the SPS1 subfamily of...
3.
Cram D, McIntosh A, Oxbrow L, Johnston A, Deaizpurua H
Differentiation
. 1999 Jun;
64(4):237-46.
PMID: 10365441
To identify genes that might play a role in growth and differentiation of pancreatic beta-cells, we have applied the technique of differential mRNA display to the lineage-related, but functionally distinct...
4.
Jiang F, Cram D, Deaizpurua H, Harrison L
Diabetes
. 1999 Apr;
48(4):722-30.
PMID: 10102687
Extracellular factors that regulate the growth and differentiation of cell lineages in the pancreatic primordia are poorly understood. Identification of these factors for pancreatic islet beta-cells could open new avenues...
5.
Schmidli R, Colman P, Cui L, Yu W, Kewming K, Jankulovski C, et al.
Autoimmunity
. 1998 Oct;
28(1):15-23.
PMID: 9754810
Insulin-dependent diabetes mellitus (IDDM) is preceded by the presence of antibodies against islet proteins including a protein tyrosine phosphatase (PTP) designated IA-2. Recently, we cloned a novel PTP named IAR...
6.
Deaizpurua H, Cram D, Naselli G, Devereux L, Dorow D
J Biol Chem
. 1997 Jun;
272(26):16364-73.
PMID: 9195943
Events controlling differentiation to insulin-secreting beta-cells in the pancreas are not well understood, although beta-cells are thought to arise from pluripotent ductal precursor cells. To search for signaling proteins that...
7.
Niwa H, Harrison L, Deaizpurua H, Cram D
Endocrinology
. 1997 Apr;
138(4):1419-26.
PMID: 9075697
A knowledge of beta cell-specific gene expression provides a basis for identifying proteins potentially involved in beta cell function and pathology. To identify candidate beta cell-specific genes, we applied the...
8.
Cui L, Yu W, Deaizpurua H, Schmidli R, Pallen C
J Biol Chem
. 1996 Oct;
271(40):24817-23.
PMID: 8798755
Cloning of the cDNA encoding a novel human protein- tyrosine phosphatase (PTP) called islet cell antigen-related PTP (IAR) predicts a receptor-like molecule with an extracellular domain of 614 amino acids...
9.
Schmidli R, Harrison L, James R, Deaizpurua H
Biochem J
. 1996 Aug;
317 ( Pt 3):713-9.
PMID: 8760354
Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease in which cytokines are thought to play an important role in beta-cell destruction and immune regulation. A major target of beta-cell autoimmunity...
10.
Schmidli R, Deaizpurua H, Harrison L, Colman P
J Autoimmun
. 1994 Feb;
7(1):55-66.
PMID: 8198702
Antibodies to glutamic decarboxylase (GADAb) are present in insulin-dependent diabetes (IDD) but their association with age and sex and their temporal profile in relation to disease onset have not been...