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L C Harrison

Explore the profile of L C Harrison including associated specialties, affiliations and a list of published articles. Areas
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Articles 275
Citations 3635
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Recent Articles
1.
Bandala-Sanchez E, Bediaga N, Naselli G, Neale A, Harrison L
Hum Immunol . 2020 Feb; 81(2-3):101-104. PMID: 32046870
Most sialic acid-binding immunoglobulin-like lectins (Siglecs) suppress immune cell function but are expressed at low levels on human T cells. We found that soluble CD52 inhibited T cell signalling by...
2.
Wallace H, Harrison L, Monteiro E, Jones R
Frontline Gastroenterol . 2017 Aug; 6(3):178-181. PMID: 28839808
A 36-year old man with known HIV infection presented to an outpatient genitourinary service with jaundice, rash and sore throat. Investigations revealed marked biochemical abnormalities, including alkaline phosphatase and alanine...
3.
Wentworth J, Zhang J, Bandala-Sanchez E, Naselli G, Liu R, Ritchie M, et al.
Int J Obes (Lond) . 2017 Aug; 41(12):1782-1789. PMID: 28769120
Background: Inflammatory factors derived from adipose tissue have been implicated in mediating insulin resistance in obesity. We sought to identify these using explanted human adipose tissue exposed to innate and...
4.
Hill Q, Harrison L, Padmakumar A, Owen R, Prasad K, Lucas G, et al.
Hematology . 2016 Oct; 22(3):162-167. PMID: 27764999
Objective And Importance: Transplantation-mediated alloimmune thrombocytopenia (TMAT) occurs when leukocytes transferred in a donor organ from a patient with immune thrombocytopenia (ITP), mount a response against recipient platelets. We present...
5.
Wentworth J, Naselli G, Ngui K, Smyth G, Liu R, OBrien P, et al.
Int J Obes (Lond) . 2015 Oct; 40(4):706-13. PMID: 26499445
Aims: The association between central obesity and insulin resistance reflects the properties of visceral adipose tissue. Our aim was to gain further insight into this association by analysing the lipid...
6.
Wentworth J, Lukic V, Bahlo M, Finlay M, Nguyen C, Morahan G, et al.
Intern Med J . 2014 Nov; 44(11):1137-40. PMID: 25367728
Exome sequencing is being increasingly used to identify disease-associated gene mutations. We used whole exome sequencing to determine the genetic basis of a syndrome of diabetes and renal disease affecting...
7.
Fourlanos S, Elkassaby S, Varney M, Colman P, Harrison L
Diabetes Res Clin Pract . 2014 Apr; 104(3):e69-71. PMID: 24698405
We hypothesised that higher body weight, a proposed risk factor for type 1 diabetes mellitus, would be associated with increased penetrance of lower risk genes. In adults at diagnosis of...
8.
Chan A, Leeansyah E, Cochrane A, dUdekem dAcoz Y, Mittag D, Harrison L, et al.
Clin Exp Immunol . 2013 Mar; 172(1):129-37. PMID: 23480193
Our understanding of human type 1 natural killer T (NKT) cells has been heavily dependent on studies of cells from peripheral blood. These have identified two functionally distinct subsets defined...
9.
Liu Y, Mitchell P, Kilpatrick T, Stein M, Harrison L, Baker J, et al.
J Clin Neurosci . 2012 Oct; 19(12):1689-94. PMID: 23084347
The initiating events in multiple sclerosis (MS) plaque formation are poorly understood. Retrospective analysis of serial imaging data can improve the understanding of tissue changes characterising acute MS lesion evolution....
10.
Micallef S, Li X, Schiesser J, Hirst C, Yu Q, Lim S, et al.
Diabetologia . 2011 Nov; 55(3):694-706. PMID: 22120512
Aims/hypothesis: We aimed to generate human embryonic stem cell (hESC) reporter lines that would facilitate the characterisation of insulin-producing (INS⁺) cells derived in vitro. Methods: Homologous recombination was used to...