H Ebisu
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Explore the profile of H Ebisu including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
37
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Recent Articles
1.
Fukuda Y, Seto S, Furuta H, Ebisu H, Oomori Y, Terashima S
J Med Chem
. 2001 Apr;
44(9):1396-406.
PMID: 11311062
We synthesized the novel seco cyclopropa[c]pyrrolo[3,2-e]indole (CPI) bisalkylators and evaluated their antitumor activity. Among these derivatives, 11a (AT-760), in which the two seco 3-methoxycarbonyl-2-trifluoromethyl CPI (MCTFCPI) moieties are connected with...
2.
Nakagomi K, Ebisu H, Sadakane Y, Fujii N, Akizawa T, Tanimura T
Biol Pharm Bull
. 2000 Aug;
23(7):879-83.
PMID: 10919370
Two angiotensin-I-converting enzyme (ACE) inhibitory peptides were isolated from a tryptic hydrolysate of human serum albumin (HSA). The peptides were identified by sequencing and other analyses as Ala-Trp and the...
3.
Obi K, Uda J, Iwase K, SUGIMOTO O, Ebisu H, Matsuda A
Bioorg Med Chem Lett
. 2000 Jul;
10(13):1451-4.
PMID: 10888330
A series of novel nikkomycin analogue inhibitors of the chitin synthase of fungal cell wall was synthesized and evaluated for their inhibitory activities. Among them, the compound having a phenanthrene...
4.
Uda J, Obi K, Iwase K, SUGIMOTO O, Ebisu H, Matsuda A
Nucleic Acids Symp Ser
. 2000 Apr;
(42):13-4.
PMID: 10780355
A series of novel nikkomycin analogs, which inhibited chitin synthase, the fungal cell wall biosynthesis enzyme, has been synthesized and evaluated their inhibitory activities.
5.
Nakagomi K, Yamada R, Ebisu H, Sadakane Y, Akizawa T, Tanimura T
FEBS Lett
. 2000 Feb;
467(2-3):235-8.
PMID: 10675545
We previously described a novel angiotensin-I-converting enzyme (ACE) inhibitory peptide, designated Acein-1, that was isolated from a tryptic hydrolysate of human plasma. We now report a second such inhibitory peptide,...
6.
Takahashi S, Ebisu H, Hirose T, Sano M, Nishimura M, Hirai K, et al.
Chemotherapy
. 2000 Feb;
46(2):122-8.
PMID: 10671763
The bactericidal activity of gatifloxacin, a new 6-fluoro-8-methoxy quinolone, was determined in a dynamic in vitro model mimicking complicated lower urinary tract infection. Strains of Pseudomonas aeruginosa and Enterococcus faecalis...
7.
Ebisu H, Nishikawa M, Tanaka M, Okazoe T, Morizawa Y, Shinyama H, et al.
J Cardiovasc Pharmacol
. 1999 Oct;
34(4):526-32.
PMID: 10511127
GA0113 is a newly developed angiotensin II (Ang II) AT1-receptor antagonist having a quinoline moiety. This study was undertaken to clarify the pharmacologic profile of GA0113. In vitro profiles of...
8.
Fukuda Y, Furuta H, Kusama Y, Ebisu H, Oomori Y, Terashima S
J Med Chem
. 1999 Apr;
42(8):1448-58.
PMID: 10212131
The seco-Cl 3-methoxycarbonyl-2-trifluoromethylcyclopropapyrroloindole (MCTFCPI) derivatives dl- and/or (S)-10 carrying various acyl moieties at the N6-position were synthesized along with their prodrugs (S)-12, and their antitumor activity was evaluated. Among these...
9.
Fukuda Y, Seto S, Furuta H, Ebisu H, Oomori Y, Terashima S
Bioorg Med Chem Lett
. 1999 Jan;
8(15):2003-4.
PMID: 9873475
The novel cyclopropapyrroloindole(CPI) bisalkylators were synthesized and their antitumor activity was evaluated. Among these derivatives, AT-760 (5a) in which the two 3-methoxycarbonyl-2-trifluoromethylCPI (MCTFCPI) moieties are connected with a 3,3'-(1,4-phenylene)diacryloyl group,...
10.
Fukuda Y, Furuta H, Kusama Y, Ebisu H, Oomori Y, Terashima S
Bioorg Med Chem Lett
. 1999 Jan;
8(11):1387-90.
PMID: 9871771
The novel 3-methoxycarbonyl-2-trifluoromethylcyclopropapyrroloindole (MCTFCPI) bisalkylators were synthesized and their antitumor activity was evaluated. Among these derivatives, 7f in which two MCTFCPI moieties are connected with a 5,5'-bis(2-carbonyl-1H-indole) group, was found...