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H Ebisu

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Articles 17
Citations 37
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11.
Nakagomi K, Fujimura A, Ebisu H, Sakai T, Sadakane Y, Fujii N, et al.
FEBS Lett . 1998 Nov; 438(3):255-7. PMID: 9827556
A novel angiotensin-I-converting enzyme (ACE) inhibitory peptide, designated acein-1, was isolated from the tryptic hydrolysate of human plasma. Gel filtration and cation exchange chromatography were performed to purify this peptide,...
12.
Kido H, Nishikawa M, Hayashi K, Kubo Y, Ebisu H, Egi Y, et al.
Nihon Yakurigaku Zasshi . 1997 Jun; 109(6):291-301. PMID: 9253776
The antihypertensive effects of AE0047, a novel 1,4-dihydropyridine-type calcium antagonist, were investigated in spontaneously hypertensive rats (SHR/crj) and two kidney-one clip renal hypertensive dogs (RHD). AE0047, which was orally administered...
13.
Kido H, Nishikawa M, Hayashi K, Kubo Y, Ohtaki Y, Fujino Y, et al.
Nihon Yakurigaku Zasshi . 1997 Jun; 109(6):279-89. PMID: 9253775
The antihypertensive effects of oral or intravenous administration of AE0047, a novel 1,4-dihydropyridine-type calcium antagonist, were investigated in spontaneously hypertensive rats (SHR/crj), one kidney-one clip renal hypertensive rats (RHR), deoxycorticosterone...
14.
Matzno S, Gohda M, Eda M, Ebisu H, Uno S, Ishida N, et al.
J Pharmacol Exp Ther . 1994 Dec; 271(3):1666-71. PMID: 7996482
Antihypertensive drugs are expected to have a lipid-lowering effect for use in treating ischemic heart disease. We evaluated the effect of (+)-N-(6-amino-3-pyridil)-N'-[(1S,2R,4R)-bicyclo-[2.2.1]hept-2-yl] -N"- cyanoguanidine hydrochloride (AL0671), a newly synthesized cyanoguanidine-derivative...
15.
Takemoto T, Eda M, Okada T, Sakashita H, Matzno S, Gohda M, et al.
J Med Chem . 1994 Jan; 37(1):18-25. PMID: 8289193
This report describes the synthesis and pharmacological evaluation of a series of novel potassium channel openers related to the pinacidil-type compounds. Thioureas, cyanoguanidines, and pyridine N-oxides were systematically evaluated for...
16.
Shinoda H, Ebisu H, Mitsuhashi J, Inaba M, Tsuruo T
Cancer Chemother Pharmacol . 1992 Jan; 30(5):335-40. PMID: 1505070
To predict the clinical effect on leukemic disease of a combination regimen developed to circumvent multidrug resistance (MDR), we tested various antitumor agents in the presence and absence of AHC-52,...
17.
Nagata Y, Ebisu H, Tamaru M, Fujita K, Koide T
J Neurochem . 1989 May; 52(5):1570-5. PMID: 2468738
We found atrial natriuretic peptide (ANP), known as a humoral factor in regulating body fluid volume and blood pressure, in considerable quantities in rat superior cervical sympathetic ganglion (SCG) by...