H-Erich Wichmann
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Explore the profile of H-Erich Wichmann including associated specialties, affiliations and a list of published articles.
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45427
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Recent Articles
1.
Blechter B, Wang X, Shi J, Shiraishi K, Choi J, Matsuo K, et al.
medRxiv
. 2024 Jul;
PMID: 38978671
Polygenic risk scores (PRSs) are promising for risk stratification but have mainly been developed in European populations. This study developed single- and multi-ancestry PRSs for lung adenocarcinoma (LUAD) in East...
2.
Wang X, Zhang Z, Ding Y, Chen T, Mucci L, Albanes D, et al.
Genome Med
. 2024 Feb;
16(1):22.
PMID: 38317189
Background: Although polygenic risk score (PRS) has emerged as a promising tool for predicting cancer risk from genome-wide association studies (GWAS), the individual-level accuracy of lung cancer PRS and the...
3.
Li Y, Xiao X, Li J, Han Y, Cheng C, Fernandes G, et al.
Cancer Epidemiol Biomarkers Prev
. 2024 Jan;
33(3):389-399.
PMID: 38180474
Background: Clinical, molecular, and genetic epidemiology studies displayed remarkable differences between ever- and never-smoking lung cancer. Methods: We conducted a stratified multi-population (European, East Asian, and African descent) association study...
4.
Du M, Xin J, Zheng R, Yuan Q, Wang Z, Liu H, et al.
Cancer Res
. 2023 Dec;
84(4):616-625.
PMID: 38117513
Significance: The causal pathway connecting CYP2A6 genetic variability and activity, cigarette consumption, and lung cancer susceptibility in smokers highlights the need for behavior modification interventions based on host susceptibility for...
5.
Zhao X, Yang M, Fan J, Wang M, Wang Y, Qin N, et al.
Cancer
. 2023 Dec;
130(6):913-926.
PMID: 38055287
Background: Although the associations between genetic variations and lung cancer risk have been explored, the epigenetic consequences of DNA methylation in lung cancer development are largely unknown. Here, the genetically...
6.
Lagou V, Jiang L, Ulrich A, Zudina L, Gonzalez K, Balkhiyarova Z, et al.
Nat Genet
. 2023 Sep;
55(9):1448-1461.
PMID: 37679419
Conventional measurements of fasting and postprandial blood glucose levels investigated in genome-wide association studies (GWAS) cannot capture the effects of DNA variability on 'around the clock' glucoregulatory processes. Here we...
7.
Shi J, Shiraishi K, Choi J, Matsuo K, Chen T, Dai J, et al.
Nat Commun
. 2023 May;
14(1):3043.
PMID: 37236969
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study...
8.
Cheng C, Hong W, Li Y, Xiao X, McKay J, Han Y, et al.
J Thorac Oncol
. 2023 May;
18(8):1003-1016.
PMID: 37150255
Introduction: Mosaic chromosomal alterations (mCAs) detected in white blood cells represent a type of clonal hematopoiesis (CH) that is understudied compared with CH-related somatic mutations. A few recent studies indicated...
9.
Peters A, Greiser K, Gottlicher S, Ahrens W, Albrecht M, Bamberg F, et al.
Eur J Epidemiol
. 2022 Oct;
37(10):1107-1124.
PMID: 36260190
The German National Cohort (NAKO) is a multidisciplinary, population-based prospective cohort study that aims to investigate the causes of widespread diseases, identify risk factors and improve early detection and prevention...
10.
Byun J, Han Y, Li Y, Xia J, Long E, Choi J, et al.
Nat Genet
. 2022 Aug;
54(8):1167-1177.
PMID: 35915169
To identify new susceptibility loci to lung cancer among diverse populations, we performed cross-ancestry genome-wide association studies in European, East Asian and African populations and discovered five loci that have...