Gyu Seong Heo
Overview
Explore the profile of Gyu Seong Heo including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
583
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0
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Recent Articles
11.
Zhang X, Detering L, Heo G, Sultan D, Luehmann H, Li L, et al.
ACS Pharmacol Transl Sci
. 2024 Jan;
7(1):285-293.
PMID: 38230294
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and treatment-refractory malignancies. The lack of an effective screening tool results in the majority of patients being diagnosed at late...
12.
Strunk M, Heo G, Hess A, Luehmann H, Ross T, Gropler R, et al.
J Nucl Med
. 2024 Jan;
65(2):287-293.
PMID: 38176717
The immune-fibrosis axis plays a critical role in cardiac remodeling after acute myocardial infarction. Imaging approaches to monitor temporal inflammation and fibroblast activation in mice have seen wide application in...
13.
Elizondo-Benedetto S, Sastriques-Dunlop S, Detering L, Arif B, Heo G, Sultan D, et al.
medRxiv
. 2023 Nov;
PMID: 37986880
Abdominal aortic aneurysm (AAA) is a degenerative vascular disease impacting aging populations with a high mortality upon rupture. There are no effective medical therapies to prevent AAA expansion and rupture....
14.
Ma P, Liu J, Qin J, Lai L, Heo G, Luehmann H, et al.
Circulation
. 2023 Sep;
149(1):48-66.
PMID: 37746718
Background: Immune checkpoint inhibitors (ICIs), antibodies targeting PD-1 (programmed cell death protein 1)/PD-L1 (programmed death-ligand 1) or CTLA4 (cytotoxic T-lymphocyte-associated protein 4), have revolutionized cancer management but are associated with...
15.
Maier A, Toner Y, Munitz J, Sullivan N, Sakurai K, Meerwaldt A, et al.
JACC Basic Transl Sci
. 2023 Aug;
8(7):801-816.
PMID: 37547068
In the past 2 decades, research on atherosclerotic cardiovascular disease has uncovered inflammation to be a key driver of the pathophysiological process. A pressing need therefore exists to quantitatively and...
16.
Ma P, Liu J, Qin J, Lai L, Heo G, Luehmann H, et al.
bioRxiv
. 2023 May;
PMID: 37162929
Background: Immune checkpoint inhibitors (ICIs), antibodies targeting PD-1/PD-L1 or CTLA4 have revolutionized cancer management but are associated with devastating immune-related adverse events (irAEs) including myocarditis. The main risk factor for...
17.
Toczek J, Gona K, Liu Y, Ahmad A, Ghim M, Ojha D, et al.
Circ Cardiovasc Imaging
. 2023 Jan;
16(1):e014615.
PMID: 36649454
Background: Matrix metalloproteinases (MMPs) play a key role in the pathogenesis of abdominal aortic aneurysm (AAA). Imaging aortic MMP activity, especially using positron emission tomography to access high sensitivity, quantitative...
18.
Heo G, Diekmann J, Thackeray J, Liu Y
Circ Cardiovasc Imaging
. 2023 Jan;
16(1):e014067.
PMID: 36649445
Inflammation is a key mechanistic contributor to the progression of cardiovascular disease, from atherosclerosis through ischemic injury and overt heart failure. Recent evidence has identified specific roles of immune cell...
19.
Liu Z, Liao F, Zhu J, Zhou D, Heo G, Leuhmann H, et al.
J Clin Invest
. 2022 Oct;
132(19).
PMID: 36189800
Bronchiolitis obliterans syndrome (BOS) is a major impediment to lung transplant survival and is generally resistant to medical therapy. Extracorporeal photophoresis (ECP) is an immunomodulatory therapy that shows promise in...
20.
Cifarelli V, Kuda O, Yang K, Liu X, Gross R, Pietka T, et al.
Front Cardiovasc Med
. 2022 Sep;
9:948332.
PMID: 36061565
CD36 mediates the uptake of long-chain fatty acids (FAs), a major energy substrate for the myocardium. Under excessive FA supply, CD36 can cause cardiac lipid accumulation and inflammation while its...