Hannah Luehmann
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Explore the profile of Hannah Luehmann including associated specialties, affiliations and a list of published articles.
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37
Citations
704
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Recent Articles
1.
Yang B, Chan M, Heo G, Lou L, Luehmann H, Park C, et al.
JHEP Rep
. 2024 Dec;
6(12):101220.
PMID: 39624233
Background & Aims: Metabolic-dysfunction associated steatohepatitis (MASH) is associated with obesity and diabetes, and is linked to liver fibrosis and cardiovascular disease. Identification of patients who have MASH is challenging...
2.
Amrute J, Luo X, Penna V, Yang S, Yamawaki T, Hayat S, et al.
Nature
. 2024 Oct;
635(8038):423-433.
PMID: 39443792
Inflammation and tissue fibrosis co-exist and are causally linked to organ dysfunction. However, the molecular mechanisms driving immune-fibroblast cell communication in human cardiac disease remain unexplored and there are at...
3.
Gallerand A, Dolfi B, Stunault M, Caillot Z, Castiglione A, Strazzulla A, et al.
Nat Commun
. 2024 Oct;
15(1):9027.
PMID: 39424804
Monocytes directly contribute to atherosclerosis development by their recruitment to plaques in which they differentiate into macrophages. In the present study, we ask how modulating monocyte glucose metabolism could affect...
4.
Lou L, Detering L, Luehmann H, Amrute J, Sultan D, Ma P, et al.
Circ Res
. 2024 Sep;
135(10):990-1003.
PMID: 39328090
Background: Immune checkpoint inhibitor (ICI) usage has resulted in immune-related adverse events in patients with cancer, such as accelerated atherosclerosis. Of immune cells involved in atherosclerosis, the role of CCR2+...
5.
Lavine K, Sultan D, Luehmann H, Detering L, Zhang X, Heo G, et al.
Nat Cardiovasc Res
. 2024 Jul;
2(10):874-880.
PMID: 38947883
Among the diverse populations of myeloid cells that reside within the healthy and diseased heart, C-C chemokine receptor 2 (CCR2) is specifically expressed on inflammatory populations of monocytes and macrophages...
6.
Zhang X, Heo G, Li A, Lahad D, Detering L, Tao J, et al.
J Nucl Med
. 2024 Mar;
65(5):775-780.
PMID: 38548349
Tissue-resident macrophages are complementary to proinflammatory macrophages to promote the progression of atherosclerosis. The noninvasive detection of their presence and dynamic variation will be important to the understanding of their...
7.
Zhang X, Detering L, Heo G, Sultan D, Luehmann H, Li L, et al.
ACS Pharmacol Transl Sci
. 2024 Jan;
7(1):285-293.
PMID: 38230294
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and treatment-refractory malignancies. The lack of an effective screening tool results in the majority of patients being diagnosed at late...
8.
Sastriques-Dunlop S, Elizondo-Benedetto S, Arif B, Meade R, Zaghloul M, Luehmann H, et al.
Sci Rep
. 2024 Jan;
14(1):1438.
PMID: 38228786
Abdominal aortic aneurysms (AAAs) are prevalent with aging, and AAA rupture is associated with increased mortality. There is currently no effective medical therapy to prevent AAA rupture. The monocyte chemoattractant...
9.
Strunk M, Heo G, Hess A, Luehmann H, Ross T, Gropler R, et al.
J Nucl Med
. 2024 Jan;
65(2):287-293.
PMID: 38176717
The immune-fibrosis axis plays a critical role in cardiac remodeling after acute myocardial infarction. Imaging approaches to monitor temporal inflammation and fibroblast activation in mice have seen wide application in...
10.
Pedersen L, Valenzuela Ripoll C, Ozcan M, Guo Z, Lotfinaghsh A, Zhang S, et al.
Med
. 2023 Nov;
4(12):928-943.e5.
PMID: 38029754
Background: Rapidly dividing cells are more sensitive to radiation therapy (RT) than quiescent cells. In the failing myocardium, macrophages and fibroblasts mediate collateral tissue injury, leading to progressive myocardial remodeling,...