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Gys J de Jongh

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Citations 275
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Recent Articles
1.
Jansen P, Kamsteeg M, Rodijk-Olthuis D, van Vlijmen-Willems I, de Jongh G, Bergers M, et al.
J Invest Dermatol . 2009 Mar; 129(9):2167-74. PMID: 19322213
The vanin gene family encodes secreted and membrane-bound ectoenzymes that convert pantetheine into pantothenic acid and cysteamine. Recent studies in a mouse colitis model indicated that vanin-1 has proinflammatory activity...
2.
Jansen P, Rodijk-Olthuis D, Hollox E, Kamsteeg M, Tjabringa G, de Jongh G, et al.
PLoS One . 2009 Mar; 4(3):e4725. PMID: 19266104
Background: Previous studies have extensively documented antimicrobial and chemotactic activities of beta-defensins. Human beta-defensin-2 (hBD-2) is strongly expressed in lesional psoriatic epidermis, and recently we have shown that high beta-defensin...
3.
Zeeuwen P, de Jongh G, Rodijk-Olthuis D, Kamsteeg M, Verhoosel R, van Rossum M, et al.
PLoS One . 2008 Jun; 3(6):e2301. PMID: 18523683
In the past decades, chronic inflammatory diseases such as psoriasis, atopic dermatitis, asthma, Crohn's disease and celiac disease were generally regarded as immune-mediated conditions involving activated T-cells and proinflammatory cytokines...
4.
Kamsteeg M, Zeeuwen P, de Jongh G, Rodijk-Olthuis D, Zeeuwen-Franssen M, van Erp P, et al.
J Invest Dermatol . 2007 Mar; 127(7):1786-9. PMID: 17363915
No abstract available.
5.
Cheng T, Hitomi K, van Vlijmen-Willems I, de Jongh G, Yamamoto K, Nishi K, et al.
J Biol Chem . 2006 Mar; 281(23):15893-9. PMID: 16565075
Cystatin M/E is a high affinity inhibitor of the asparaginyl endopeptidase legumain, and we have previously reported that both proteins are likely to be involved in the regulation of stratum...
6.
de Jongh G, Zeeuwen P, Kucharekova M, Pfundt R, Van der Valk P, Blokx W, et al.
J Invest Dermatol . 2005 Dec; 125(6):1163-73. PMID: 16354186
Recently, it was shown that lesional skin of atopic dermatitis patients expresses low levels of some antimicrobial peptides, compared with psoriasis patients. Here we performed microarray analysis on mRNA from...
7.
Franssen M, de Jongh G, van Erp P, van de Kerkhof P
Acta Derm Venereol . 2004 Jun; 84(3):195-200. PMID: 15202835
Vitamin D3 analogues are a first-line treatment of chronic plaque psoriasis, but so far, comparative clinical studies on calcipotriol and calcitriol ointment are sparse, and in particular no comparative studies...
8.
Zeeuwen P, Dale B, de Jongh G, van Vlijmen-Willems I, Fleckman P, Kimball J, et al.
J Invest Dermatol . 2003 Jul; 121(1):65-8. PMID: 12839564
Cystatin M/E is a recently discovered cysteine proteinase inhibitor whose expression is largely confined to cutaneous epithelia. In human skin it is expressed in sweat glands, hair follicles, and stratum...
9.
van Ruissen F, Jansen B, de Jongh G, Zeeuwen P, Schalkwijk J
Genomics . 2002 May; 79(5):671-8. PMID: 11991716
Serial analysis of gene expression (SAGE) is a powerful technique for global expression profiling without prior knowledge of the genes of interest. We carried out SAGE analysis of purified keratinocytes...
10.
van Ruissen F, Jansen B, de Jongh G, van Vlijmen-Willems I, Schalkwijk J
FASEB J . 2002 Jan; 16(2):246-8. PMID: 11772949
Serial analysis of gene expression (SAGE) has been used for quantitative analysis of gene expression. We applied cluster analysis on multiple SAGE libraries derived from premalignant epidermal tissue (actinic keratosis),...