Diana Rodijk-Olthuis
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Explore the profile of Diana Rodijk-Olthuis including associated specialties, affiliations and a list of published articles.
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Citations
698
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Recent Articles
1.
Arnold K, Moran M, Shi H, van Vlijmen-Willems I, Rodijk-Olthuis D, Smits J, et al.
Exp Dermatol
. 2024 May;
33(5):e15084.
PMID: 38711223
The transmembrane protein claudin-1 is critical for formation of the epidermal barrier structure called tight junctions (TJ) and has been shown to be important in multiple disease states. These include...
2.
van den Brink N, Pardow F, Meesters L, van Vlijmen-Willems I, Rodijk-Olthuis D, Niehues H, et al.
J Invest Dermatol
. 2024 Apr;
144(11):2488-2500.e4.
PMID: 38642800
Three-dimensional human epidermal equivalents (HEEs) are a state-of-the-art organotypic culture model in preclinical investigative dermatology and regulatory toxicology. In this study, we investigated the utility of electrical impedance spectroscopy (EIS)...
3.
Smits J, Qu J, Pardow F, van den Brink N, Rodijk-Olthuis D, van Vlijmen-Willems I, et al.
J Invest Dermatol
. 2024 Feb;
144(9):2013-2028.e2.
PMID: 38401701
The aryl hydrocarbon receptor (AHR) is an evolutionary conserved environmental sensor identified as an indispensable regulator of epithelial homeostasis and barrier organ function. Molecular signaling cascade and target genes upon...
4.
Rikken G, Meesters L, Jansen P, Rodijk-Olthuis D, van Vlijmen-Willems I, Niehues H, et al.
Microbiome
. 2023 Oct;
11(1):227.
PMID: 37849006
Background: Following descriptive studies on skin microbiota in health and disease, mechanistic studies on the interplay between skin and microbes are on the rise, for which experimental models are in...
5.
Smits J, Qu J, Pardow F, van den Brink N, Rodijk-Olthuis D, van Vlijmen-Willems I, et al.
bioRxiv
. 2023 Jun;
PMID: 37333234
The aryl hydrocarbon receptor (AHR) is an evolutionary conserved environmental sensor identified as indispensable regulator of epithelial homeostasis and barrier organ function. Molecular signaling cascade and target genes upon AHR...
6.
van der Krieken D, Rikken G, Ederveen T, Jansen P, Rodijk-Olthuis D, Meesters L, et al.
iScience
. 2023 Apr;
26(4):106483.
PMID: 37096035
In atopic dermatitis (AD), chronic skin inflammation is associated with skin barrier defects and skin microbiome dysbiosis including a lower abundance of Gram-positive anaerobic cocci (GPACs). We here report that,...
7.
Smits J, van den Brink N, Meesters L, Hamdaoui H, Niehues H, Jansen P, et al.
J Invest Dermatol
. 2023 Mar;
143(8):1520-1528.e5.
PMID: 36893939
Ever since the association between FLG loss-of-function variants and ichthyosis vulgaris and atopic dermatitis disease onset was identified, FLGs function has been under investigation. Intraindividual genomic predisposition, immunological confounders, and...
8.
Niehues H, Rikken G, Kersten F, Eeftens J, van Vlijmen-Willems I, Rodijk-Olthuis D, et al.
J Invest Dermatol
. 2023 Feb;
143(8):1498-1508.e7.
PMID: 36804407
Late cornified envelope (LCE) proteins are small cationic epidermal proteins with antimicrobial properties, and the combined deletion of LCE3B and LCE3C genes is a risk factor for psoriasis that affects...
9.
Niehues H, Rikken G, van Vlijmen-Willems I, Rodijk-Olthuis D, van Erp P, Zeeuwen P, et al.
JID Innov
. 2022 Feb;
2(1):100066.
PMID: 35146480
Psoriasis and atopic dermatitis are chronic inflammatory skin diseases characterized by keratinocyte (KC) hyperproliferation and epidermal acanthosis (hyperplasia). The milieu of disease-associated cytokines and soluble factors is considered a mitogenic...
10.
Niehues H, Jansen P, Rodijk-Olthuis D, Rikken G, Smits J, Schalkwijk J, et al.
Exp Dermatol
. 2020 Jun;
29(7):672-676.
PMID: 32506526
In biomedical research, cell culture contamination is one of the main culprits of experimental failure. Contamination sources and concomitant remedies are numerous and challenging to manage. We herein describe two...