Guy T Carter
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Explore the profile of Guy T Carter including associated specialties, affiliations and a list of published articles.
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63
Citations
1752
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Recent Articles
1.
Kirk R, He H, Wahome P, Wu S, Carter G, Bertin M
ACS Omega
. 2021 Jun;
6(23):15472-15478.
PMID: 34151125
Metabolite mining of environmentally collected aquatic and marine microbiomes offers a platform for the discovery of new therapeutic lead molecules. Combining a prefractionated chromatography library with liquid chromatography tandem mass...
2.
He H, Bertin M, Wu S, Wahome P, Beauchesne K, Youngs R, et al.
J Nat Prod
. 2018 Oct;
81(11):2576-2581.
PMID: 30369239
Cyanobufalins A-C (1-3), a new series of cardiotoxic steroids, have been discovered from cyanobacterial blooms in Buckeye Lake and Grand Lake St. Marys in Ohio. Compounds 1-3 contain distinctive structural...
3.
He H, Wu S, Wahome P, Bertin M, Pedone A, Beauchesne K, et al.
J Nat Prod
. 2018 May;
81(6):1368-1375.
PMID: 29847132
Four new microcystin congeners are described including the first three examples of microcystins containing the rare doubly homologated tyrosine residue 2-amino-5-(4-hydroxyphenyl)pentanoic acid (Ahppa) (1-4). Large-scale harvesting and biomass processing allowed...
4.
Wlodek A, Kendrew S, Coates N, Hold A, Pogwizd J, Rudder S, et al.
Nat Commun
. 2017 Nov;
8(1):1206.
PMID: 29089518
Erythromycin, avermectin and rapamycin are clinically useful polyketide natural products produced on modular polyketide synthase multienzymes by an assembly-line process in which each module of enzymes in turn specifies attachment...
5.
Moore B, Carter G, Bronstrup M
Nat Prod Rep
. 2017 Jul;
34(7):685-686.
PMID: 28671218
No abstract available.
6.
Harms H, Kurita K, Pan L, Wahome P, He H, Kinghorn A, et al.
Bioorg Med Chem Lett
. 2016 Sep;
26(20):4960-4965.
PMID: 27641470
Cyanobacteria possess a unique capacity for the production of structurally novel secondary metabolites compared to the biosynthetic abilities of other environmental prokaryotes such as bacteria of the genus Streptomyces. Two...
7.
Jadulco R, Koch M, Kakule T, Schmidt E, Orendt A, He H, et al.
J Nat Prod
. 2014 Oct;
77(11):2537-44.
PMID: 25351193
Three new decalin-type tetramic acid analogues, pyrrolocins A (1), B (2), and C (3), were defined as products of a metabolic pathway from a fern endophyte, NRRL 50135, from Papua...
8.
Janso J, Haltli B, Eustaquio A, Kulowski K, Waldman A, Zha L, et al.
Tetrahedron
. 2014 Jul;
70(27-28):4156-4164.
PMID: 25045187
The lomaiviticins are a family of cytotoxic marine natural products that have captured the attention of both synthetic and biological chemists due to their intricate molecular scaffolds and potent biological...
9.
Carter G
Nat Prod Rep
. 2014 Jan;
31(6):711-7.
PMID: 24468674
This Highlight explores the evolution of applications of mass spectrometric technologies in the context of natural products research since the 1970's. The central themes are the analysis of mixtures, dereplication...
10.
Di L, Kerns E, Carter G
Expert Opin Drug Discov
. 2013 Mar;
3(6):677-87.
PMID: 23506148
Background: The principles and screening strategies for brain penetration in drug discovery are important in identifying drug candidates with desirable CNS properties. Objective: Define key variables and assays that are...