Guru R Valicherla
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Explore the profile of Guru R Valicherla including associated specialties, affiliations and a list of published articles.
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25
Citations
176
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Recent Articles
1.
Dadge S, Syed A, Husain A, Valicherla G, Gayen J
Molecules
. 2023 Jun;
28(12).
PMID: 37375211
is a nutrient-rich plant with a history of use in traditional medicine. It boasts a diverse range of polyphenols, including quercetin, resveratrol, β-sitosterol, myricetin, and other compounds. We developed and...
2.
Zheng R, Valicherla G, Zhang J, Nuttall J, Silvera P, Marshall L, et al.
Pharmaceutics
. 2022 Sep;
14(9).
PMID: 36145696
The dapivirine (DPV) vaginal ring was developed by the nonprofit International Partnership for Microbicides (IPM) for reducing the risk of HIV infection. A clinical study (IPM 028) showed that concomitant...
3.
Husain A, Makadia V, Valicherla G, Riyazuddin M, Gayen J
Drug Dev Res
. 2022 Feb;
83(4):825-841.
PMID: 35103340
P-glycoprotein (P-gp) is a transporter protein that is come under the ATP binding cassette family of proteins. It is situated on the surface of the intestine epithelium, where P-gp substrate...
4.
Valicherla G, Katekar R, Dadge S, Riyazuddin M, Syed A, Singh S, et al.
Molecules
. 2022 Jan;
27(2).
PMID: 35056659
PSTi8 is a pancreastatin inhibitory peptide that is effective in the treatment of diabetic models. This study investigates the pharmacokinetic (PK) properties of PSTi8 in Sprague Dawley rats, for the...
5.
Hu M, Valicherla G, Zhou T, Hillier S, Rohan L
AIDS Res Hum Retroviruses
. 2021 Feb;
38(1):22-32.
PMID: 33567990
Phosphorylating enzymes (PEs) are responsible for activating nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) such as tenofovir (TFV) and are critical for their conversion to obtain intracellular antiviral activity. However, there are...
6.
Singh S, Valicherla G, Bikkasani A, Cheruvu S, Hossain Z, Taneja I, et al.
J Ethnopharmacol
. 2021 Jan;
270:113819.
PMID: 33460762
Ethnopharmacological Relevance: Withanone (WN), an active constituent of Withania somnifera commonly called Ashwagandha has remarkable pharmacological responses along with neurological activities. However, for a better understanding of the pharmacokinetic and...
7.
Gupta A, Garg R, Singh P, Goand U, Syed A, Valicherla G, et al.
Eur J Pharmacol
. 2020 May;
881:173204.
PMID: 32439261
Pancreastatin (PST), a chromogranin A (CHGA) derived peptide connects obesity with insulin resistance by inducing inflammation. Previously, we have evaluated potential activity of PST inhibitor (PSTi8) in liver and adipose...
8.
Valicherla G, Riyazuddin M, Shahi S, Gupta A, Syed A, Husain A, et al.
J Pharm Biomed Anal
. 2020 Jan;
180:113074.
PMID: 31891874
PSTi8 is a 21 amino acid pancreastatin inhibitory peptide that demonstrated potent antidiabetic activity in insulin resistant rodent models. The goal of the current work is to establish and validate...
9.
Riyazuddin M, Husain A, Valicherla G, Verma S, Gupta A, Praveena K, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2019 Nov;
1130-1131:121829.
PMID: 31670104
S011-2111 is a semicarbazone and chalcone hybrid demonstrating antiproliferative tumor cell-selective effects along with unique antimetastatic potential by mitigating PP2A-β-catenin signalling pathway. The present study envisaged to explore the in...
10.
Gupta A, Syed A, Garg R, Goand U, Singh P, Riyazuddin M, et al.
Eur J Pharmacol
. 2019 Oct;
864:172723.
PMID: 31586632
Pancreastatin (PST), a chromogranin A derived peptide has anti-insulin effects and plays a significant role in obesity-induced insulin resistance. In obesity and type 2 diabetes mellitus, both insulin and PST...