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Guro E Lind

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Articles 69
Citations 3039
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Recent Articles
1.
Kresse S, Brandt-Winge S, Pharo H, Flatin B, Jeanmougin M, Vedeld H, et al.
Clin Epigenetics . 2023 Sep; 15(1):151. PMID: 37710283
Background: DNA methylation biomarkers in circulating cell-free DNA (cfDNA) have great clinical potential for cancer management. Most methods for DNA methylation analysis require bisulfite conversion, causing DNA degradation and loss....
2.
Pinto R, Hauge T, Jeanmougin M, Pharo H, Kresse S, Honne H, et al.
Clin Epigenetics . 2022 Jun; 14(1):77. PMID: 35701814
Background: Despite the efforts to describe the molecular landscape of esophageal adenocarcinoma (EAC) and its precursor lesion Barrett's esophagus (BE), discrepant findings are reported. Here, we investigated the prevalence of...
3.
Namlos H, Skarn M, Ahmed D, Grad I, Andresen K, Kresse S, et al.
BMC Genomics . 2022 Feb; 23(1):142. PMID: 35172717
Background: Osteosarcoma is the most common primary malignant tumour of bone occurring in children and young adolescents and is characterised by complex genetic and epigenetic changes. The miRNA miR-486-5p has...
4.
Vedeld H, Grimsrud M, Andresen K, Pharo H, von Seth E, Karlsen T, et al.
Hepatology . 2021 Aug; 75(1):59-73. PMID: 34435693
Background And Aims: Primary sclerosing cholangitis (PSC) is associated with increased risk of cholangiocarcinoma (CCA). Early and accurate CCA detection represents an unmet clinical need as the majority of patients...
5.
Flatin B, Vedeld H, Pinto R, Langerud J, Lind G, Lothe R, et al.
Int J Cancer . 2020 Dec; 148(7):1652-1657. PMID: 33284993
Intratumor heterogeneity of colorectal cancers (CRCs) is manifested both at the genomic and epigenomic levels. Early genetic aberrations in carcinogenesis are clonal and present throughout the tumors, but less is...
6.
Jeanmougin M, Havik A, Cekaite L, Brandal P, Sveen A, Meling T, et al.
Mol Oncol . 2020 Mar; 14(5):1016-1027. PMID: 32171051
Glioblastoma (GBM), the most aggressive form of brain cancer, is characterized by a high level of molecular heterogeneity, and infiltration by various immune and stromal cell populations. Important advances have...
7.
Marcuello M, Vymetalkova V, Neves R, Duran-Sanchon S, Vedeld H, Tham E, et al.
Mol Aspects Med . 2019 Jun; 69:107-122. PMID: 31189073
New non-invasive approaches that can complement and improve on current strategies for colorectal cancer (CRC) screening and management are urgently needed. A growing number of publications have documented that components...
8.
Vedeld H, Nesbakken A, Lothe R, Lind G
Clin Epigenetics . 2018 Jun; 10:70. PMID: 29854011
We have previously shown that aberrant promoter methylation of is a potential biomarker for colorectal cancer detection with high sensitivity (71%) and specificity (98%). This finding was recently confirmed by...
9.
Pharo H, Andresen K, Berg K, Lothe R, Jeanmougin M, Lind G
Clin Epigenetics . 2018 Feb; 10:24. PMID: 29484034
Background: Droplet digital PCR (ddPCR) allows absolute quantification of nucleic acids and has potential for improved non-invasive detection of DNA methylation. For increased precision of the methylation analysis, we aimed...
10.
Vedeld H, Goel A, Lind G
Semin Cancer Biol . 2017 Dec; 51:36-49. PMID: 29253542
Each year, almost 4.1 million people are diagnosed with gastrointestinal (GI) cancers. Due to late detection of this disease, the mortality is high, causing approximately 3 million cancer-related deaths annually,...