Hege Marie Vedeld
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Explore the profile of Hege Marie Vedeld including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
462
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Recent Articles
1.
Pinto R, Vedeld H, Lind G, Jeanmougin M
Mol Oncol
. 2024 Dec;
PMID: 39696831
In this study, we propose an alternative approach for stratifying genome-scale DNA methylation profiles of gastrointestinal (GI) adenocarcinomas based on a robust analytical framework. A set of 978 GI adenocarcinomas...
2.
Vedeld H, Pharo H, Sorbo A, Brandt-Winge S, Five M, Jeanmougin M, et al.
Mol Oncol
. 2024 May;
18(11):2684-2695.
PMID: 38720532
Cystoscopy is the gold standard for surveillance of non-muscle invasive bladder cancer (NMIBC), but the procedure is invasive and has suboptimal accuracy. The aim of this study was to investigate...
3.
Kresse S, Brandt-Winge S, Pharo H, Flatin B, Jeanmougin M, Vedeld H, et al.
Clin Epigenetics
. 2023 Sep;
15(1):151.
PMID: 37710283
Background: DNA methylation biomarkers in circulating cell-free DNA (cfDNA) have great clinical potential for cancer management. Most methods for DNA methylation analysis require bisulfite conversion, causing DNA degradation and loss....
4.
Jeanmougin M, Brodal H, Dietrichson Pharo H, Vedeld H, Lind G
Bioinformatics
. 2022 Nov;
39(1).
PMID: 36448696
Motivation: Droplet digital PCR (ddPCR) holds great promises for investigating DNA methylation with high sensitivity. Yet, the lack of methods for analyzing ddPCR DNA methylation data has resulted in users...
5.
Dietrichson Pharo H, Jeanmougin M, Ager-Wick E, Vedeld H, Sorbo A, Dahl C, et al.
Clin Epigenetics
. 2022 Sep;
14(1):115.
PMID: 36115961
Background: Cystoscopy is the gold standard for bladder cancer detection, but is costly, invasive and has imperfect diagnostic accuracy. We aimed to identify novel and accurate DNA methylation biomarkers for...
6.
Vedeld H, Grimsrud M, Andresen K, Pharo H, von Seth E, Karlsen T, et al.
Hepatology
. 2021 Aug;
75(1):59-73.
PMID: 34435693
Background And Aims: Primary sclerosing cholangitis (PSC) is associated with increased risk of cholangiocarcinoma (CCA). Early and accurate CCA detection represents an unmet clinical need as the majority of patients...
7.
Flatin B, Vedeld H, Pinto R, Langerud J, Lind G, Lothe R, et al.
Int J Cancer
. 2020 Dec;
148(7):1652-1657.
PMID: 33284993
Intratumor heterogeneity of colorectal cancers (CRCs) is manifested both at the genomic and epigenomic levels. Early genetic aberrations in carcinogenesis are clonal and present throughout the tumors, but less is...
8.
Vedeld H, Folseraas T, Lind G
JHEP Rep
. 2020 Sep;
2(5):100143.
PMID: 32939446
Cholangiocarcinoma (CCA) is a highly fatal malignancy of the bile ducts that arises in up to 20% of patients with primary sclerosing cholangitis (PSC). Current detection methods for CCA display...
9.
Marcuello M, Vymetalkova V, Neves R, Duran-Sanchon S, Vedeld H, Tham E, et al.
Mol Aspects Med
. 2019 Jun;
69:107-122.
PMID: 31189073
New non-invasive approaches that can complement and improve on current strategies for colorectal cancer (CRC) screening and management are urgently needed. A growing number of publications have documented that components...
10.
Vedeld H, Nesbakken A, Lothe R, Lind G
Clin Epigenetics
. 2018 Jun;
10:70.
PMID: 29854011
We have previously shown that aberrant promoter methylation of is a potential biomarker for colorectal cancer detection with high sensitivity (71%) and specificity (98%). This finding was recently confirmed by...