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Gunnar Dittmar

Explore the profile of Gunnar Dittmar including associated specialties, affiliations and a list of published articles. Areas
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Articles 133
Citations 8066
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Recent Articles
1.
Mendes M, Borrmann K, Dittmar G
Expert Rev Proteomics . 2024 Oct; 21(9-10):367-376. PMID: 39435569
Introduction: The introduction of trapped ion mobility spectrometry (TIMS) in combination with fast high-resolution time-of-flight (TOF) mass spectrometry to the proteomics field led to a jump in protein identifications and...
2.
Martin E, Girardello R, Dittmar G, Ludwig A
Elife . 2024 Sep; 13. PMID: 39315773
Caveolae are small membrane pits with fundamental roles in mechanotransduction. Several studies have shown that caveolae flatten out in response to increased membrane tension, thereby acting as a mechanosensitive membrane...
3.
Schmidt A, Zhang H, Schmitt S, Rausch C, Popp O, Chen J, et al.
Cells . 2024 Jan; 13(2). PMID: 38247831
Pericentric heterochromatin (PCH) forms spatio-temporarily distinct compartments and affects chromosome organization and stability. Albeit some of its components are known, an elucidation of its proteome and how it differs between...
4.
Glover H, Mendes M, Gomes-Neto J, Rusilowicz-Jones E, Rigden D, Dittmar G, et al.
J Cell Sci . 2023 Dec; 137(2). PMID: 38149663
The microtubule network is formed from polymerised tubulin subunits and associating proteins, which govern microtubule dynamics and a diverse array of functions. To identify novel microtubule-binding proteins, we have developed...
5.
Siegel F, Schmidt H, Juneja M, Smith J, Herrmann P, Kobelt D, et al.
Front Oncol . 2023 Dec; 13:1280977. PMID: 38144523
Background: Identification of cancer metastasis-relevant molecular networks is desired to provide the basis for understanding and developing intervention strategies. Here we address the role of GIPC1 in the process of...
6.
Zhang J, Keibler M, Dong W, Ghelfi J, Cordes T, Kanashova T, et al.
Biomedicines . 2023 Oct; 11(10). PMID: 37893215
Using an untargeted stable isotope-assisted metabolomics approach, we identify erythronate as a metabolite that accumulates in several human cancer cell lines. Erythronate has been reported to be a detoxification product...
7.
Perez-Hernandez D, Suarez-Artiles L, Jones M, Dittmar G
STAR Protoc . 2023 Sep; 4(4):102549. PMID: 37756153
Here, we provide a protocol for the systematic screening of protein-protein interactions mediated by short linear motifs using the Protein Interaction Screen on a peptide Matrix (PrISMa) technique. We describe...
8.
Cirzi C, Dyckow J, Legrand C, Schott J, Guo W, Perez Hernandez D, et al.
EMBO J . 2023 Aug; 42(19):e112507. PMID: 37609797
Queuosine (Q) is a modified nucleoside at the wobble position of specific tRNAs. In mammals, queuosinylation is facilitated by queuine uptake from the gut microbiota and is introduced into tRNA...
9.
Boeddrich A, Haenig C, Neuendorf N, Blanc E, Ivanov A, Kirchner M, et al.
Genome Med . 2023 Jul; 15(1):50. PMID: 37468900
Background: Alzheimer's disease (AD) is characterized by the intra- and extracellular accumulation of amyloid-β (Aβ) peptides. How Aβ aggregates perturb the proteome in brains of patients and AD transgenic mouse...
10.
Perez-Hernandez D, Jones M, Dittmar G
Methods Mol Biol . 2023 Jul; 2690:269-280. PMID: 37450154
Protein-protein interactions (PPI) are essential to understanding the cellular function and key mechanisms necessary for life. Although understanding of the interactome and proteome has exploded due to high-throughput methods in...