Gunilla Olivecrona
Overview
Explore the profile of Gunilla Olivecrona including associated specialties, affiliations and a list of published articles.
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101
Citations
3015
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Recent Articles
1.
Modder M, In Het Panhuis W, Li M, Afkir S, Dorn A, Pronk A, et al.
Cardiovasc Res
. 2024 Sep;
120(17):2179-2190.
PMID: 39259836
Aims: Angiopoietin-like 3 (ANGPTL3) and 4 (ANGPTL4) inhibit lipoprotein lipase to regulate tissue fatty acid (FA) uptake from triglyceride (TG)-rich lipoproteins such as very low density lipoproteins (VLDL). While pharmacological...
2.
Rioja J, Ariza M, Benitez-Toledo M, Espildora-Hernandez J, Coca-Prieto I, Arrobas-Velilla T, et al.
J Clin Lipidol
. 2023 Feb;
17(2):272-280.
PMID: 36813655
Background: Activity assays for lipoprotein lipase (LPL) are not standardised for use in clinical settings. Objective: This study sought to define and validate a cut-off points based on a ROC...
3.
Nyren R, Scherman H, Axelsson J, Chang C, Olivecrona G, Ericsson M
PLoS One
. 2023 Feb;
18(2):e0281705.
PMID: 36787333
It is known that high-fat diet (HFD) and/or diabetes may influence substrate preferences and energy demands in the heart preceding diabetic cardiomyopathy. They may also induce structural glomerular changes causing...
4.
Deng M, Kutrolli E, Sadewasser A, Michel S, Joibari M, Jaschinski F, et al.
J Lipid Res
. 2022 Jun;
63(7):100237.
PMID: 35667416
Angiopoietin-like 4 (ANGPTL4) is an important regulator of plasma triglyceride (TG) levels and an attractive pharmacological target for lowering plasma lipids and reducing cardiovascular risk. Here, we aimed to study...
5.
Kovrov O, Landfors F, Saar-Kovrov V, Naslund U, Olivecrona G
J Lipid Res
. 2021 Oct;
63(1):100144.
PMID: 34710432
LPL is a key player in plasma triglyceride metabolism. Consequently, LPL is regulated by several proteins during synthesis, folding, secretion, and transport to its site of action at the luminal...
6.
Ruppert P, Michielsen C, Hazebroek E, Pirayesh A, Olivecrona G, Afman L, et al.
Mol Metab
. 2020 Jun;
40:101033.
PMID: 32504883
Objective: Studies in mice have shown that the decrease in lipoprotein lipase (LPL) activity in adipose tissue upon fasting is mediated by induction of the inhibitor ANGPTL4. Here, we aimed...
7.
Kristensen K, Leth-Espensen K, Mertens H, Birrane G, Meiyappan M, Olivecrona G, et al.
Proc Natl Acad Sci U S A
. 2020 Feb;
117(8):4337-4346.
PMID: 32034094
The binding of lipoprotein lipase (LPL) to GPIHBP1 focuses the intravascular hydrolysis of triglyceride-rich lipoproteins on the surface of capillary endothelial cells. This process provides essential lipid nutrients for vital...
8.
Jarvie E, Stewart F, Ramsay J, Brown E, Meyer B, Olivecrona G, et al.
J Clin Endocrinol Metab
. 2019 Dec;
105(3).
PMID: 31832635
Context: Maternal body mass index (BMI) is associated with increased birth weight but does not explain all the variance in fetal adiposity. Objective: To assess the contribution of maternal body...
9.
Oteng A, Ruppert P, Boutens L, Dijk W, van Dierendonck X, Olivecrona G, et al.
J Lipid Res
. 2019 Aug;
60(10):1741-1754.
PMID: 31409739
Angiopoietin-like protein (ANGPTL)4 regulates plasma lipids, making it an attractive target for correcting dyslipidemia. However, ANGPTL4 inactivation in mice fed a high fat diet causes chylous ascites, an acute-phase response,...
10.
Nyren R, Makoveichuk E, Malla S, Kersten S, Nilsson S, Ericsson M, et al.
Am J Physiol Renal Physiol
. 2019 Jan;
316(3):F558-F571.
PMID: 30698048
Activity of lipoprotein lipase (LPL) is high in mouse kidney, but the reason is poorly understood. The aim was to characterize localization, regulation, and function of LPL in kidney of...