Guanglin Chen
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Explore the profile of Guanglin Chen including associated specialties, affiliations and a list of published articles.
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63
Citations
561
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Recent Articles
11.
Munoz E, Chen G, Hossain A, Wu S, Oceguera Nava E, Hang J, et al.
Bioorg Med Chem Lett
. 2022 Jun;
72:128870.
PMID: 35772635
Roughly 268,000 new cases of prostate cancer and 34,000 deaths from prostate cancer are projected by the American Cancer Society to occur in the United States in 2022. Androgen receptor...
12.
Liu D, Shi H, Chen G, Zhang X, Gu T, Zhu M, et al.
Extremophiles
. 2022 Jun;
26(2):22.
PMID: 35767155
High metal ion concentrations and low pH cause severely inhibit the activity of an acidophilic microbial consortium (AMC) in bioleaching. This work investigated the effects of exogenous spermine on biofilm...
13.
Li X, Li S, Zhou P, Chen G
Entropy (Basel)
. 2022 Apr;
24(4).
PMID: 35455141
In this paper, we propose a broad learning system based on the sparrow search algorithm. Firstly, in order to avoid the complicated manual parameter tuning process and obtain the best...
14.
Jiang W, Chen G, Wang Y, Zhong W, Zhou C, Zhang J, et al.
Front Pediatr
. 2022 Feb;
10:813865.
PMID: 35186808
Objectives: The aim of this study was to identify predictors for enteral autonomy and intestinal failure (IF)-related complications and evaluate the outcomes of a multi-center pediatric cohort in China. Methods:...
15.
Rangel V, Gu L, Chen G, Chen Q, Xue L
Bioorg Med Chem Lett
. 2022 Feb;
61:128608.
PMID: 35143982
Herein, we present a class of potent triplex DNA binding ligands derived from the natural product quercetin, which is the first of its kind that has ever been reported in...
16.
Wu S, Chen G, Zhang Q, Wang G, Chen Q
Molecules
. 2021 Nov;
26(21).
PMID: 34770829
To search for novel androgen receptor (AR) modulators for the potential treatment of castration-resistant prostate cancer (CRPC), naturally occurring silibinin was sought after as a lead compound because it possesses...
17.
Zhu Z, Jiang W, Li W, Zhang J, Lv X, Lu C, et al.
Neurol Sci
. 2021 Jun;
43(2):1067-1070.
PMID: 34089111
Objective: There is little evidence to support a correlation between abdominal surgery and acute cerebellar ataxia (ACA). We reviewed the records of children with ACA treated at our institution to...
18.
Chen T, Qin Y, Chen M, Zhang Y, Wang X, Dong T, et al.
BMC Med
. 2021 May;
19(1):120.
PMID: 34039350
Background: Gestational diabetes mellitus (GDM) is a metabolic disease that occurs in pregnant women and increases the risk for the development of diabetes. The relationship between GDM and meconium microbiota...
19.
Chen G, Gonzalez M, Jiang Z, Zhang Q, Wang G, Chen Q
Bioorg Med Chem Lett
. 2021 Mar;
40:127970.
PMID: 33753258
(-)-Zampanolide is a unique microtubule stabilizing agent (MSA) with covalent-binding mechanism and low nanomolar anitproliferative potency towards multi-drug resistant cancer cells. MSAs have a special connection with prostate cancer by...
20.
Hao Q, Wang P, Dutta P, Chung S, Li Q, Wang K, et al.
Cell Death Dis
. 2020 Dec;
11(12):1052.
PMID: 33311440
The abnormal PI3K/AKT/mTOR pathway is one of the most common genomic abnormalities in breast cancers including triple-negative breast cancer (TNBC), and pharmacologic inhibition of these aberrations has shown activity in...