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Gregory Seumois

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Articles 84
Citations 3904
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Recent Articles
1.
Da Silva Antunes R, Fajardo-Rosas V, Yu E, Galvez R, Abawi A, Escarrega E, et al.
bioRxiv . 2025 Jan; PMID: 39829792
The long-term effects of repeated COVID-19 vaccinations on adaptive immunity remain incompletely understood. Here, we conducted a comprehensive three-year longitudinal study examining T cell and antibody responses in 78 vaccinated...
2.
Dantzer J, Lewis S, Psoter K, Sutherland A, Frazier A, Richardson E, et al.
JCI Insight . 2025 Jan; 10(1. PMID: 39782691
BACKGROUNDCow's milk (CM) allergy is the most common food allergy in young children. Treatment with oral immunotherapy (OIT) has shown efficacy, but high rates of adverse reactions. The aim of...
3.
Kang N, Chawla A, Hillman H, Tippalagama R, Kim C, Mikulski Z, et al.
bioRxiv . 2024 Oct; PMID: 39386643
Communication between immune cells through direct contact is a critical feature of immune responses. Here, we developed a novel high-throughput method to study the transcriptome and adaptive immune receptor repertoire...
4.
Hogan N, Castaneda-Castro F, Ramamoorthy Premlal A, Brickner H, Mondal M, Herrera-De La Mata S, et al.
J Leukoc Biol . 2024 Aug; 116(6):1420-1431. PMID: 39136235
E-cigarette use has become widespread, and its effects on airway inflammation and disease are not fully delineated. E-cigarette vapor extract (EVE) profoundly affects neutrophil function. We hypothesized that EVE also...
5.
Li Y, Ramirez-Suastegui C, Harris R, Castaneda-Castro F, Ascui G, Perez-Jeldres T, et al.
Nat Immunol . 2024 Jun; 25(7):1231-1244. PMID: 38898157
To understand the role of T cells in the pathogenesis of ulcerative colitis (UC), we analyzed colonic T cells isolated from patients with UC and controls. Here we identified colonic...
6.
Van Espen B, Prideaux E, Wilson A, Machado C, Sendo S, Parker J, et al.
Arthritis Rheumatol . 2024 Apr; 76(8):1243-1251. PMID: 38556917
Objective: Rheumatoid arthritis (RA) is an autoimmune disease in which the joint lining or synovium becomes highly inflamed and majorly contributes to disease progression. Understanding pathogenic processes in RA synovium...
7.
Miller A, Kosaloglu-Yalcin Z, Westernberg L, Montero L, Bahmanof M, Frentzen A, et al.
Sci Transl Med . 2024 Feb; 16(736):eabj9905. PMID: 38416845
The clinical impact of tumor-specific neoantigens as both immunotherapeutic targets and biomarkers has been impeded by the lack of efficient methods for their identification and validation from routine samples. We...
8.
Brunel S, Picarda G, Gupta A, Ghosh R, McDonald B, El Morabiti R, et al.
PLoS Pathog . 2024 Jan; 20(1):e1011852. PMID: 38236791
Conventional antiviral memory CD4 T cells typically arise during the first two weeks of acute infection. Unlike most viruses, cytomegalovirus (CMV) exhibits an extended persistent replication phase followed by lifelong...
9.
Upadhye A, Meza Landeros K, Ramirez-Suastegui C, Schmiedel B, Woo E, Chee S, et al.
Nat Cancer . 2024 Jan; 5(5):791-807. PMID: 38228835
Brain tumors in children are a devastating disease in a high proportion of patients. Owing to inconsistent results in clinical trials in unstratified patients, the role of immunotherapy remains unclear....
10.
Naftel J, Mistry H, Mitchell F, Belson J, Kyyaly M, Barber C, et al.
J Asthma Allergy . 2023 Dec; 16:1333-1345. PMID: 38144877
Background: Despite most of the asthma population having mild disease, the mild asthma phenotype is poorly understood. Here, we aim to address this gap in knowledge by extensively characterising the...