Christian H Ottensmeier
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Explore the profile of Christian H Ottensmeier including associated specialties, affiliations and a list of published articles.
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101
Citations
10724
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Recent Articles
1.
Varley M, Euden J, Adams R, Barnes E, Bodman C, Choy E, et al.
BMJ Open
. 2025 Jan;
15(1):e084345.
PMID: 39832967
Introduction: Despite repeated vaccinations against SARS-CoV-2 virus, patients who are immunocompromised remain at very high risk of catching SARS-CoV-2 virus and becoming unwell. AZD7442 (Evusheld) is a long-acting monoclonal antibody...
2.
von Witzleben A, Grages A, Thomas J, Ezic J, Brunner C, Schuler P, et al.
Oral Oncol
. 2024 Nov;
159:107107.
PMID: 39549431
Introduction: A substantial proportion of head and neck squamous cell carcinoma (HNSCC), particularly oropharyngeal squamous cell carcinoma (OPSCC), is associated with human papillomavirus (HPV), resulting in distinct molecular phenotypes. In...
3.
Zager J, Orloff M, Ferrucci P, Choi J, Eschelman D, Glazer E, et al.
Ann Surg Oncol
. 2024 Jul;
31(12):8262-8263.
PMID: 39026142
No abstract available.
4.
Zager J, Orloff M, Ferrucci P, Choi J, Eschelman D, Glazer E, et al.
Ann Surg Oncol
. 2024 May;
31(8):5340-5351.
PMID: 38704501
Background: Uveal melanoma (UM) has a poor prognosis once liver metastases occur. The melphalan/Hepatic Delivery System (melphalan/HDS) is a drug/device combination used for liver-directed treatment of metastatic UM (mUM) patients....
5.
Martin M, Aguilar-Rosas S, Franke K, Pieterse M, van Langelaar J, Schreurs R, et al.
Cancer Immunol Res
. 2024 Apr;
12(6):759-778.
PMID: 38573707
Identification of immunogenic cancer neoantigens as targets for therapy is challenging. Here, we integrate the whole-genome and long-read transcript sequencing of cancers to identify the collection of neo-open reading frame...
6.
Kors T, Hofmann L, Betzler A, Payer K, Bens M, Truong J, et al.
Cancer Res Commun
. 2024 Feb;
4(2):571-587.
PMID: 38329386
Significance: Patients with HPV-negative OPSCC have a poorer prognosis due to distinct molecular pathways. This study reveals significant transcriptomic differences between HPV-negative and HPV-positive OPSCC, identifying INHBA as a key...
7.
Upadhye A, Meza Landeros K, Ramirez-Suastegui C, Schmiedel B, Woo E, Chee S, et al.
Nat Cancer
. 2024 Jan;
5(5):791-807.
PMID: 38228835
Brain tumors in children are a devastating disease in a high proportion of patients. Owing to inconsistent results in clinical trials in unstratified patients, the role of immunotherapy remains unclear....
8.
Chandra S, Ascui G, Riffelmacher T, Chawla A, Ramirez-Suastegui C, Castelan V, et al.
Sci Immunol
. 2023 Nov;
8(89):eabn8531.
PMID: 37948512
Mucosal-associated invariant T (MAIT) cells are a subset of T lymphocytes that respond to microbial metabolites. We defined MAIT cell populations in different organs and characterized the developmental pathway of...
9.
von Witzleben A, Ellis M, Thomas G, Hoffmann T, Jackson R, Laban S, et al.
Clin Cancer Res
. 2023 Oct;
30(1):224-234.
PMID: 37874322
Purpose: High numbers of tumor-infiltrating lymphocytes (TIL) are linked to better survival in patients with cancer. Tissue-resident memory T cells (TRM; CD8+CD103+) are recognized as a key player of anticancer...
10.
Gray S, Ottensmeier C
Cancers (Basel)
. 2023 Oct;
15(19).
PMID: 37835491
Non-small cell lung cancer (NSCLC) remains a cause of significant morbidity and mortality, despite significant advances made in its treatment using immune checkpoint inhibitors (ICIs) over the last decade; while...