Gregory R Mundy
Overview
Explore the profile of Gregory R Mundy including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
68
Citations
5216
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Edwards J, Mundy G
Nat Rev Rheumatol
. 2011 Mar;
7(4):235-43.
PMID: 21386794
The maintenance of adequate bone mass is dependent upon the controlled and timely removal of old, damaged bone. This complex process is performed by the highly specialized, multinucleated osteoclast. Over...
12.
Johnson R, Nguyen M, Padalecki S, Grubbs B, Merkel A, Oyajobi B, et al.
Cancer Res
. 2010 Dec;
71(3):822-31.
PMID: 21189326
Breast cancer frequently metastasizes to bone, in which tumor cells receive signals from the bone marrow microenvironment. One relevant factor is TGF-β, which upregulates expression of the Hedgehog (Hh) signaling...
13.
Ruppender N, Merkel A, Martin T, Mundy G, Sterling J, Guelcher S
PLoS One
. 2010 Nov;
5(11):e15451.
PMID: 21085597
Nearly 70% of breast cancer patients with advanced disease will develop bone metastases. Once established in bone, tumor cells produce factors that cause changes in normal bone remodeling, such as...
14.
Longitudinal live animal micro-CT allows for quantitative analysis of tumor-induced bone destruction
Johnson L, Johnson R, Munoz S, Mundy G, Peterson T, Sterling J
Bone
. 2010 Aug;
48(1):141-51.
PMID: 20685406
The majority of breast cancer and prostate cancer patients with metastatic disease will go on to develop bone metastases, which contribute largely to the patient's morbidity and mortality. Numerous small...
15.
Sterling J, Edwards J, Martin T, Mundy G
Bone
. 2010 Jul;
48(1):6-15.
PMID: 20643235
It is increasingly evident that the microenvironment of bone can influence the cancer phenotype in many ways that favor growth in bone. The ability of cancer cells to adhere to...
16.
Yang L, Edwards C, Mundy G
J Bone Miner Res
. 2010 Jun;
25(8):1701-6.
PMID: 20572008
The growth and metastasis of solid tumors not only depends on their ability to escape from immune surveillance but also hinges on their ability to invade the vasculature system as...
17.
Ganapathy V, Ge R, Grazioli A, Xie W, Banach-Petrosky W, Kang Y, et al.
Mol Cancer
. 2010 May;
9:122.
PMID: 20504320
Background: Transforming Growth Factor beta (TGF-beta) plays an important role in tumor invasion and metastasis. We set out to investigate the possible clinical utility of TGF-beta antagonists in a human...
18.
Edwards J, Nyman J, Lwin S, Moore M, Esparza J, OQuinn E, et al.
J Bone Miner Res
. 2010 May;
25(11):2419-26.
PMID: 20499365
Transforming growth factor β (TGF-β) is an abundant bone matrix protein that influences osteoblast and osteoclast interactions to control bone remodeling. As such, TGF-β represents an obvious pharmacologic target with...
19.
Coleman R, Lipton A, Roodman G, Guise T, Boyce B, Brufsky A, et al.
Cancer Treat Rev
. 2010 May;
36(8):615-20.
PMID: 20478658
Tumor metastasis to the skeleton affects over 400,000 individuals in the United States annually, more than any other site of metastasis, including significant proportions of patients with breast, prostate, lung...
20.
Yoshii T, Hafeman A, Nyman J, Esparza J, Shinomiya K, Spengler D, et al.
Tissue Eng Part A
. 2010 Mar;
16(7):2369-79.
PMID: 20205517
Scaffolds prepared from biodegradable polyurethanes (PUR) have been investigated as a supportive matrix and delivery system for skin, cardiovascular, and bone tissue engineering. In this study, we combined reactive two-component...