Gregory M Barton
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Explore the profile of Gregory M Barton including associated specialties, affiliations and a list of published articles.
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57
Citations
5966
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Recent Articles
1.
Pestal K, Slayden L, Barton G
J Exp Med
. 2025 Mar;
222(5).
PMID: 40072341
Tissue-resident macrophages adopt distinct gene expression profiles and exhibit functional specialization based on their tissue of residence. Recent studies have begun to define the signals and transcription factors that induce...
2.
Eislmayr K, Langner C, Liu F, Yuvaraj S, Babirye J, Roncaioli J, et al.
bioRxiv
. 2025 Feb;
PMID: 39896533
Bacteria of the genus replicate in intestinal epithelial cells and cause shigellosis, a severe diarrheal disease that resolves spontaneously in most healthy individuals. During shigellosis, neutrophils are abundantly recruited to...
3.
Hamerman J, Barton G
Curr Opin Immunol
. 2024 Oct;
91:102482.
PMID: 39353255
Five mammalian Toll-like receptors (TLR 3, 7, 8, 9, and 13) recognize nucleic acids (NA) and induce signals that control the function of multiple immune cell types and initiate both...
4.
Rael V, Yano J, Huizar J, Slayden L, Weiss M, Turcotte E, et al.
J Exp Med
. 2024 May;
221(8).
PMID: 38780621
Nucleic acid-sensing Toll-like receptors (TLR) 3, 7/8, and 9 are key innate immune sensors whose activities must be tightly regulated to prevent systemic autoimmune or autoinflammatory disease or virus-associated immunopathology....
5.
Carroll S, Pasare C, Barton G
Immunity
. 2024 Apr;
57(4):632-648.
PMID: 38599163
One of the most significant conceptual advances in immunology in recent history is the recognition that signals from the innate immune system are required for induction of adaptive immune responses....
6.
Pestal K, Slayden L, Barton G
bioRxiv
. 2024 Mar;
PMID: 38464159
Tissue-resident macrophages adopt distinct gene expression profiles and exhibit functional specialization based on their tissue of residence. Recent studies have begun to define the signals and transcription factors that induce...
7.
Raso F, Liu S, Simpson M, Barton G, Mayer C, Acharya M, et al.
Immunity
. 2023 Sep;
56(10):2373-2387.e8.
PMID: 37714151
Immunoglobulin A (IgA) maintains commensal communities in the intestine while preventing dysbiosis. IgA generated against intestinal microbes assures the simultaneous binding to multiple, diverse commensal-derived antigens. However, the exact mechanisms...
8.
Davey L, Malkus P, Villa M, Dolat L, Holmes Z, Letourneau J, et al.
Nat Microbiol
. 2023 Jun;
8(8):1450-1467.
PMID: 37337046
Akkermansia muciniphila, a mucophilic member of the gut microbiota, protects its host against metabolic disorders. Because it is genetically intractable, the mechanisms underlying mucin metabolism, gut colonization and its impact...
9.
Lind N, Rael V, Pestal K, Liu B, Barton G
Nat Rev Immunol
. 2021 Jul;
22(4):224-235.
PMID: 34272507
Many of the ligands for Toll-like receptors (TLRs) are unique to microorganisms, such that receptor activation unequivocally indicates the presence of something foreign. However, a subset of TLRs recognizes nucleic...
10.
Becken B, Davey L, Middleton D, Mueller K, Sharma A, Holmes Z, et al.
mBio
. 2021 May;
12(3).
PMID: 34006653
The mucophilic anaerobic bacterium is a prominent member of the gastrointestinal (GI) microbiota and the only known species of the phylum in the mammalian gut. A high prevalence of in...