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Gregg Duester

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Articles 103
Citations 4987
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Recent Articles
1.
Duester G
Curr Top Dev Biol . 2025 Jan; 161():1-32. PMID: 39870430
All-trans RA (ATRA) is a small molecule derived from retinol (vitamin A) that directly controls gene expression at the transcriptional level by serving as a ligand for nuclear ATRA receptors....
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Duester G
Front Neuroendocrinol . 2023 Aug; 71:101099. PMID: 37647946
It is well established that retinoic acid receptors (RARs) function as nuclear receptors that control gene expression in response to binding of the ligand retinoic acid (RA). However, some studies...
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Berenguer M, Duester G
J Mol Endocrinol . 2022 May; 69(4):T59-T67. PMID: 35593389
Vitamin A (retinol) is an important nutrient for embryonic development and adult health. Early studies identified retinoic acid (RA) as a metabolite of retinol, however, its importance was not apparent....
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Duester G
J Neurol Disord . 2022 Apr; 10(1). PMID: 35382260
Retinoic acid (RA) is the active form of vitamin A that functions as a ligand for nuclear RA receptors that directly bind genomic control regions to regulate gene expression. However,...
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Duester G
Cells . 2022 Feb; 11(3). PMID: 35159132
Retinoic acid (RA) functions as an essential signal for development of the vertebrate eye by controlling the transcriptional regulatory activity of RA receptors (RARs). During eye development, the optic vesicles...
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Petrosino J, Longenecker J, Ramkumar S, Xu X, Dorn L, Bratasz A, et al.
J Clin Invest . 2021 Feb; 131(4). PMID: 33586683
The relationship between adiposity and metabolic health is well established. However, very little is known about the fat depot, known as paracardial fat (pCF), located superior to and surrounding the...
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Berenguer M, Duester G
Biomolecules . 2021 Jan; 11(1). PMID: 33435477
The function of retinoic acid (RA) during limb development is still debated, as loss and gain of function studies led to opposite conclusions. With regard to limb initiation, genetic studies...
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Berenguer M, Meyer K, Yin J, Duester G
PLoS Biol . 2020 May; 18(5):e3000719. PMID: 32421711
Identification of target genes that mediate required functions downstream of transcription factors is hampered by the large number of genes whose expression changes when the factor is removed from a...