Graham J Dockray
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Explore the profile of Graham J Dockray including associated specialties, affiliations and a list of published articles.
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61
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1662
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Recent Articles
21.
Gamble J, Kenny S, Dockray G
Regul Pept
. 2013 Jul;
185:9-13.
PMID: 23816469
The intestinal hormone cholecystokinin (CCK) delays gastric emptying and inhibits food intake by actions on vagal afferent neurons. Recent studies suggest plasminogen activator inhibitor (PAI)-1 suppresses the effect of CCK...
22.
Holmberg C, Ghesquiere B, Impens F, Gevaert K, Kumar J, Cash N, et al.
J Proteome Res
. 2013 May;
12(7):3413-22.
PMID: 23705892
Cancer progression involves changes in extracellular proteolysis, but the contribution of stromal cell secretomes to the cancer degradome remains uncertain. We have now defined the secretome of a specific stromal...
23.
Kenny S, Steele I, Lyons S, Moore A, Murugesan S, Tiszlavicz L, et al.
Am J Physiol Gastrointest Liver Physiol
. 2013 Mar;
304(9):G814-22.
PMID: 23494120
Gastric mucosal health is maintained in response to potentially damaging luminal factors. Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) disrupt protective mechanisms leading to bleeding and ulceration. The plasminogen activator system...
24.
Kenny S, Gamble J, Lyons S, Vlatkovic N, Dimaline R, Varro A, et al.
Endocrinology
. 2012 Dec;
154(2):718-26.
PMID: 23254194
The adipokine plasminogen activator inhibitor (PAI)-1 is increased in plasma of obese individuals and exhibits increased expression in the stomachs of individuals infected with Helicobacter. To investigate the relevance of...
25.
Dockray G, Moore A, Varro A, Pritchard D
Curr Gastroenterol Rep
. 2012 Sep;
14(6):453-9.
PMID: 22983899
C-terminally amidated gastrins act at cholecystokinin-2 receptors (CCK2R), which are normally expressed by gastric parietal and enterochromaffin-like (ECL) cells and smooth muscle; there is also extensive expression in the CNS...
26.
Holmberg C, Quante M, Steele I, Kumar J, Balabanova S, Duval C, et al.
Carcinogenesis
. 2012 May;
33(8):1553-62.
PMID: 22610072
Tumor progression has been linked to changes in the stromal environment. Myofibroblasts are stromal cells that are often increased in tumors but their contribution to cancer progression is not well...
27.
Jones R, McKie S, Astbury N, Little T, Tivey S, Lassman D, et al.
Gut
. 2012 Feb;
61(11):1543-51.
PMID: 22315469
Objective: Gut-derived humoural factors activate central nervous system (CNS) mechanisms controlling energy intake and expenditure, and autonomic outflow. Ghrelin is secreted from the stomach and stimulates food intake and gastric...
28.
Dockray G
Curr Opin Endocrinol Diabetes Obes
. 2011 Dec;
19(1):8-12.
PMID: 22157397
Purpose Of Review: Cholecystokinin (CCK) controls nutrient delivery to the small intestine by inhibiting food intake and gastric emptying. This review deals with recent work shedding new light on how...
29.
Norsett K, Steele I, Duval C, Sammut S, Murugesan S, Kenny S, et al.
Am J Physiol Gastrointest Liver Physiol
. 2011 Jan;
301(3):G446-53.
PMID: 21193525
Plasminogen activator inhibitor (PAI)-1 is associated with cancer progression, fibrosis and thrombosis. It is expressed in the stomach but the mechanisms controlling its expression there, and its biological role, are...
30.
de Lartigue G, Lur G, Dimaline R, Varro A, Raybould H, Dockray G
Endocrinology
. 2010 Jun;
151(8):3589-99.
PMID: 20534729
Food intake is regulated by signals from peripheral organs, but the way these are integrated remains uncertain. Cholecystokinin (CCK) from the intestine and leptin from adipocytes interact to inhibit food...