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D Mark Pritchard

Explore the profile of D Mark Pritchard including associated specialties, affiliations and a list of published articles. Areas
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Articles 99
Citations 2185
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Recent Articles
1.
Tardajos Ayllon B, Bowden N, Souilhol C, Darwish H, Tian S, Duckworth C, et al.
Cardiovasc Res . 2025 Feb; PMID: 39982773
Aims: Atherosclerosis initiation at sites of disturbed blood flow involves heightened inflammation coupled to excessive endothelial cell (EC) proliferation. Here, we unveil the pivotal role of c-REL, a member of...
2.
Than N, Pritchard D, Hughes D, Duckworth C, Wong H, Haq M, et al.
Int J Radiat Oncol Biol Phys . 2024 Dec; PMID: 39674328
Purpose: Radical surgery following neoadjuvant therapy is the standard of care for locally advanced rectal cancer. A contact x-ray brachytherapy (CXB) boost can alternatively be used to treat residual disease...
3.
Than N, Pritchard D, Hughes D, Yu K, Minnaar H, Dhadda A, et al.
Clin Transl Radiat Oncol . 2024 Sep; 49:100851. PMID: 39308635
Background And Purpose: Radical surgery is the standard of care for early rectal cancer. However, alternative organ-preserving approaches are attractive, especially in frail or elderly patients as these avoid surgical...
4.
Than N, Pritchard D, Hughes D, Duckworth C, Wong H, Haq M, et al.
Radiother Oncol . 2024 Jul; 199:110465. PMID: 39074538
Background And Purpose: External Beam Radiotherapy (EBRT) followed by Contact X-ray Brachytherapy (CXB) and vice versa are viable alternatives to surgery for selected rectal cancer patients who have small tumours...
5.
Than N, Pritchard D, Duckworth C, Hughes D, Wong H, Sripadam R, et al.
J Contemp Brachytherapy . 2024 May; 16(2):95-102. PMID: 38808203
Purpose: A watch-and-wait approach is an alternative to surgery for rectal cancer patients who have achieved a clinical complete response (cCR) following neoadjuvant (chemo)radiotherapy. However, approximately 25-38% of patients experience...
6.
Hooper J, Jervis N, Morgan L, Beckett V, Hand P, Higgs K, et al.
J Neuroendocrinol . 2024 Mar; 36(4):e13380. PMID: 38471798
People with neuroendocrine neoplasms (NENs) face a multitude of challenges, including delayed diagnosis, low awareness of the cancer among healthcare professionals and limited access to multidisciplinary care and expert centres....
7.
Khan M, Cook K, Weickert M, Davies L, Pritchard D, Day M, et al.
Support Care Cancer . 2024 Feb; 32(3):199. PMID: 38421441
Purpose: PREF-NET reported patients' experience of Somatuline® (lanreotide) Autogel® (LAN) administration at home and in hospital among patients with gastroenteropancreatic neuroendocrine tumours (GEP-NETs). Methods: PREF-NET was a multicentre, cross-sectional study...
8.
Gall L, Jardi F, Lammens L, Pinero J, Souza T, Rodrigues D, et al.
CPT Pharmacometrics Syst Pharmacol . 2023 Aug; 12(10):1511-1528. PMID: 37621010
We have built a quantitative systems toxicology modeling framework focused on the early prediction of oncotherapeutic-induced clinical intestinal adverse effects. The model describes stem and progenitor cell dynamics in the...
9.
Panzuto F, Ramage J, Pritchard D, van Velthuysen M, Schrader J, Begum N, et al.
J Neuroendocrinol . 2023 Jul; 35(8):e13306. PMID: 37401795
The aim of the present guidance paper was to update the previous ENETS guidelines on well-differentiated gastric and duodenal neuroendocrine tumours (NETs), providing practical guidance for specialists in the diagnosis...
10.