Graham J Dockray
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Explore the profile of Graham J Dockray including associated specialties, affiliations and a list of published articles.
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Recent Articles
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Calvigioni D, Mate Z, Fuzik J, Girach F, Zhang M, Varro A, et al.
Cereb Cortex
. 2016 Apr;
27(4):2453-2468.
PMID: 27102657
Although extensively studied postnatally, the functional differentiation of cholecystokinin (CCK)-containing interneurons en route towards the cerebral cortex during fetal development is incompletely understood. Here, we used CCKBAC/DsRed mice encoding a...
13.
Kumar J, Kandola S, Tiszlavicz L, Reisz Z, Dockray G, Varro A
Br J Cancer
. 2016 Apr;
114(10):1152-9.
PMID: 27092781
Background: Stromal cells, including cancer-associated myofibroblasts (CAMs), are recognised to be determinants of cancer progression, but the mechanisms remain uncertain. The chemokine-like protein, chemerin, is upregulated in oesophageal squamous cancer...
14.
Wang L, Steele I, Kumar J, Dimaline R, Jithesh P, Tiszlavicz L, et al.
Am J Physiol Gastrointest Liver Physiol
. 2016 Mar;
310(9):G696-704.
PMID: 26939869
Stromal cells influence epithelial function in both health and disease. Myofibroblasts are abundant stromal cells that influence the cellular microenvironment by release of extracellular matrix (ECM) proteins, growth factors, proteases,...
15.
Kumar J, Holmberg C, Balabanova S, Borysova L, Burdyga T, Beynon R, et al.
PLoS One
. 2015 Oct;
10(10):e0141331.
PMID: 26513261
Mesenchymal stem cells (MSCs) play important roles in tissue repair and cancer progression. Our recent work suggests that some mesenchymal cells, notably myofibroblasts exhibit regulated exocytosis resembling that seen in...
16.
Kumar J, Steele I, Moore A, Murugesan S, Rakonczay Z, Venglovecz V, et al.
Am J Physiol Gastrointest Liver Physiol
. 2015 May;
309(2):G78-86.
PMID: 25977510
The pyloric antral hormone gastrin plays a role in remodeling of the gastric epithelium, but the specific targets of gastrin that mediate these effects are poorly understood. Glandular epithelial cells...
17.
Kumar J, Holmberg C, Kandola S, Steele I, Hegyi P, Tiszlavicz L, et al.
PLoS One
. 2014 Aug;
9(7):e104877.
PMID: 25127029
Stromal cells such as myofibroblasts influence tumor progression. The mechanisms are unclear but may involve effects on both tumor cells and recruitment of bone marrow-derived mesenchymal stromal cells (MSCs) which...
18.
Balabanova S, Holmberg C, Steele I, Ebrahimi B, Rainbow L, Burdyga T, et al.
Carcinogenesis
. 2014 Apr;
35(8):1798-806.
PMID: 24710625
Stromal cells influence cancer progression. Myofibroblasts are an important stromal cell type, which influence the tumour microenvironment by release of extracellular matrix (ECM) proteins, proteases, cytokines and chemokines. The mechanisms...
19.
Dockray G
J Physiol
. 2014 Feb;
592(14):2927-41.
PMID: 24566540
The landmark discovery by Bayliss and Starling in 1902 of the first hormone, secretin, emerged from earlier observations that a response (pancreatic secretion) following a stimulus (intestinal acidification) occurred after...
20.
Dockray G
Curr Opin Pharmacol
. 2013 Sep;
13(6):954-8.
PMID: 24064396
Nutrient delivery to the gut activates neuroendocrine mechanisms that control digestion and energy intake and utilisation. These include the release from enteroendocrine cells of mediators including 5HT, CCK, GLP-1, PYY...