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Gordon D Pusch

Explore the profile of Gordon D Pusch including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 14522
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Recent Articles
1.
Wattam A, Bowers N, Brettin T, Conrad N, Cucinell C, Davis J, et al.
Methods Mol Biol . 2024 May; 2802:547-571. PMID: 38819571
As genomic and related data continue to expand, research biologists are often hampered by the computational hurdles required to analyze their data. The National Institute of Allergy and Infectious Diseases...
2.
Olson R, Assaf R, Brettin T, Conrad N, Cucinell C, Davis J, et al.
Nucleic Acids Res . 2022 Nov; 51(D1):D678-D689. PMID: 36350631
The National Institute of Allergy and Infectious Diseases (NIAID) established the Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the growing body of genome sequence and other omics-related...
3.
VanOeffelen M, Nguyen M, Aytan-Aktug D, Brettin T, Dietrich E, Kenyon R, et al.
Brief Bioinform . 2021 Aug; 22(6). PMID: 34379107
Antimicrobial resistance (AMR) is a major global health threat that affects millions of people each year. Funding agencies worldwide and the global research community have expended considerable capital and effort...
4.
Parrello B, Butler R, Chlenski P, Pusch G, Overbeek R
PLoS One . 2021 Apr; 16(4):e0250092. PMID: 33857229
Large amounts of metagenomically-derived data are submitted to PATRIC for analysis. In the future, we expect even more jobs submitted to PATRIC will use metagenomic data. One in-demand use case...
5.
Davis J, Wattam A, Aziz R, Brettin T, Butler R, Butler R, et al.
Nucleic Acids Res . 2019 Nov; 48(D1):D606-D612. PMID: 31667520
The PathoSystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious Diseases (https://www.patricbrc.org). PATRIC supports bioinformatic analyses of all bacteria...
6.
Parrello B, Butler R, Chlenski P, Olson R, Overbeek J, Pusch G, et al.
BMC Bioinformatics . 2019 Oct; 20(1):486. PMID: 31581946
Background: Recent advances in high-volume sequencing technology and mining of genomes from metagenomic samples call for rapid and reliable genome quality evaluation. The current release of the PATRIC database contains...
7.
Wattam A, Brettin T, Davis J, Gerdes S, Kenyon R, Machi D, et al.
Methods Mol Biol . 2017 Dec; 1704:79-101. PMID: 29277864
In the "big data" era, research biologists are faced with analyzing new types that usually require some level of computational expertise. A number of programs and pipelines exist, but acquiring...
8.
McNair K, Aziz R, Pusch G, Overbeek R, Dutilh B, Edwards R
Methods Mol Biol . 2017 Nov; 1681:231-238. PMID: 29134599
Phages are complex biomolecular machineries that have to survive in a bacterial world. Phage genomes show many adaptations to their lifestyle such as shorter genes, reduced capacity for redundant DNA...
9.
Antonopoulos D, Assaf R, Aziz R, Brettin T, Bun C, Conrad N, et al.
Brief Bioinform . 2017 Oct; 20(4):1094-1102. PMID: 28968762
The Pathosystems Resource Integration Center (PATRIC, www.patricbrc.org) is designed to provide researchers with the tools and services that they need to perform genomic and other 'omic' data analyses. In response...
10.
Faria J, Edirisinghe J, Davis J, Disz T, Hausmann A, Henry C, et al.
3 Biotech . 2017 Mar; 5(1):101-105. PMID: 28324362
For many scientific applications, it is highly desirable to be able to compare metabolic models of closely related genomes. In this short report, we attempt to raise awareness to the...