Gordana Vunjak-Novakovic
Overview
Explore the profile of Gordana Vunjak-Novakovic including associated specialties, affiliations and a list of published articles.
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340
Citations
13863
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Recent Articles
1.
Dutta A, Rodriguez-Calero A, Ronaldson-Bouchard K, Offermann A, Rahman D, Vhatkar T, et al.
Mol Cancer Res
. 2025 Feb;
PMID: 39907729
Metastasis accounts for the overwhelming majority of cancer deaths. In prostate cancer and many other solid tumors, progression to metastasis is associated with drastically reduced survival outcomes, yet the mechanisms...
2.
Mir M, Chen J, Patel A, Pinezich M, Hudock M, Yoon A, et al.
Acta Biomater
. 2025 Jan;
194:270-287.
PMID: 39870150
In injured and diseased tissues, changes in molecular and cellular compositions, as well as tissue architecture, lead to alterations in both physiological and physical characteristics. Notably, the electrical properties of...
3.
Wang B, Morsink M, Kim S, Luo L, Zhang X, Soni R, et al.
J Clin Invest
. 2025 Jan;
135(1).
PMID: 39744939
Loss of Bcl2-associated athanogene 3 (BAG3) is associated with dilated cardiomyopathy (DCM). BAG3 regulates sarcomere protein turnover in cardiomyocytes; however, the function of BAG3 in other cardiac cell types is...
4.
Chen J, Patel A, Mir M, Hudock M, Pinezich M, Guenthart B, et al.
Adv Healthc Mater
. 2024 Oct;
14(1):e2401918.
PMID: 39440644
Ionizable lipid nanoparticles (LNPs) are pivotal in combating COVID-19, and numerous preclinical and clinical studies have highlighted their potential in nucleic acid-based therapies and vaccines. However, the effectiveness of endosomal...
5.
Baldassarri I, Tavakol D, Graney P, Chramiec A, Hibshoosh H, Vunjak-Novakovic G
Proc Natl Acad Sci U S A
. 2024 Oct;
121(42):e2405257121.
PMID: 39374382
Incomplete understanding of metastatic disease mechanisms continues to hinder effective treatment of cancer. Despite remarkable advancements toward the identification of druggable targets, treatment options for patients in remission following primary...
6.
Fleischer S, Nash T, Tamargo M, Lock R, Venturini G, Morsink M, et al.
Nat Cardiovasc Res
. 2024 Aug;
3(9):1123-1139.
PMID: 39195859
Systemic lupus erythematosus (SLE) is a heterogenous autoimmune disease that affects multiple organs, including the heart. The mechanisms of myocardial injury in SLE remain poorly understood. In this study, we...
7.
Cordoves E, Ferrari G, Zorn E, Bacha E, Vunjak-Novakovic G, Kalfa D
Med
. 2024 Aug;
5(8):859-862.
PMID: 39127035
Heart valve disease patients undergo multiple surgeries to replace structurally degraded valve prostheses, highlighting the need for valve replacements with growth and self-repair capacity. Given allogeneic valve transplantation's promise in...
8.
Kusoglu A, Ornek D, Dansik A, Uzun C, Nur Ozkan S, Sarica S, et al.
Adv Sci (Weinh)
. 2024 Jul;
11(36):e2309966.
PMID: 39083319
Tumor extracellular matrices (ECM) exhibit aberrant changes in composition and mechanics compared to normal tissues. Proteoglycans (PG) are vital regulators of cellular signaling in the ECM with the ability to...
9.
Wu Q, Rafatian N, Wagner K, Blamer J, Smith J, Okhovatian S, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(28):e2403581121.
PMID: 38968108
Adverse cardiac outcomes in COVID-19 patients, particularly those with preexisting cardiac disease, motivate the development of human cell-based organ-on-a-chip models to recapitulate cardiac injury and dysfunction and for screening of...
10.
Tavakol D, Nash T, Kim Y, Graney P, Liberman M, Fleischer S, et al.
Adv Sci (Weinh)
. 2024 Jul;
11(42):e2401415.
PMID: 38965824
Galactic cosmic radiation (GCR) is one of the most serious risks posed to astronauts during missions to the Moon and Mars. Experimental models capable of recapitulating human physiology are critical...