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Glenn L Wilson

Explore the profile of Glenn L Wilson including associated specialties, affiliations and a list of published articles. Areas
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Articles 58
Citations 1895
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Recent Articles
1.
Yuzefovych L, Kahn A, Schuler M, Eide L, Arora R, Wilson G, et al.
Cancer Res . 2021 Jun; 81(11):3144. PMID: 34087783
No abstract available.
2.
Tan Y, Pastukh V, Gorodnya O, Mulekar M, Simmons J, Machuca T, et al.
J Surg Res . 2019 Aug; 245:273-280. PMID: 31421373
Background: Transplantation of lungs procured after donation after circulatory death (DCD) is challenging because postmortem metabolic degradation may engender susceptibility to ischemia-reperfusion (IR) injury. Because oxidative mitochondrial DNA (mtDNA) damage...
3.
Bradley J, Li Z, Organ C, Polhemus D, Otsuka H, Islam K, et al.
Am J Physiol Heart Circ Physiol . 2017 Nov; 314(2):H311-H321. PMID: 29101177
Oxidative stress results in mtDNA damage and contributes to myocardial cell death. mtDNA repair enzymes are crucial for mtDNA repair and cell survival. We investigated a novel, mitochondria-targeted fusion protein...
4.
Lee Y, Obiako B, Gorodnya O, Ruchko M, Kuck J, Pastukh V, et al.
Shock . 2017 Jan; 48(1):54-60. PMID: 28125528
Although studies in rat cultured pulmonary artery endothelial cells, perfused lungs, and intact mice support the concept that oxidative mitochondrial (mt) DNA damage triggers acute lung injury (ALI), it has...
5.
Guarini G, Kiyooka T, Ohanyan V, Pung Y, Marzilli M, Chen Y, et al.
Basic Res Cardiol . 2016 Apr; 111(3):29. PMID: 27040114
Mitochondrial dysfunction in obesity and diabetes can be caused by excessive production of free radicals, which can damage mitochondrial DNA. Because mitochondrial DNA plays a key role in the production...
6.
Stopka S, Wilson G, Pearsall A
J Surg Orthop Adv . 2016 Jan; 24(4):209-12. PMID: 26731382
The hypothesis was that agents delivered intra-articularly after knee arthroscopy will be diluted by residual arthroscopic fluid. Diagnostic arthroscopy was performed on six cadaver knees. Each procedure was followed by...
7.
Yuzefovych L, Kahn A, Schuler M, Eide L, Arora R, Wilson G, et al.
Cancer Res . 2015 Nov; 76(1):30-4. PMID: 26586787
Production of mitochondrial reactive oxygen species and integrity of mitochondrial DNA (mtDNA) are crucial in breast cancer progression and metastasis. Therefore, we evaluated the role of mtDNA damage in breast...
8.
Fayzulin R, Perez M, Kozhukhar N, Spadafora D, Wilson G, Alexeyev M
Nucleic Acids Res . 2015 Mar; 43(9):e62. PMID: 25820427
Mutations in human mitochondrial DNA (mtDNA) can cause mitochondrial disease and have been associated with neurodegenerative disorders, cancer, diabetes and aging. Yet our progress toward delineating the precise contributions of...
9.
Yang X, Cui L, White J, Kuck J, Ruchko M, Wilson G, et al.
Basic Res Cardiol . 2015 Jan; 110(2):3. PMID: 25595210
Recent reports indicate that elevating DNA glycosylase/AP lyase repair enzyme activity offers marked cytoprotection in cultured cells and a variety of injury models. In this study, we measured the effect...
10.
Shokolenko I, Wilson G, Alexeyev M
World J Exp Med . 2014 Nov; 4(4):46-57. PMID: 25414817
The mitochondrial theory of aging, a mainstream theory of aging which once included accumulation of mitochondrial DNA (mtDNA) damage by reactive oxygen species (ROS) as its cornerstone, has been increasingly...