Giovanna Bergamini
Overview
Explore the profile of Giovanna Bergamini including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
2220
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0
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Recent Articles
1.
Alkhalaf L, Arrowsmith C, Balskus E, Bergamini G, Bhandari R, Chang C, et al.
Nat Chem Biol
. 2024 Dec;
21(1):6-15.
PMID: 39719500
No abstract available.
2.
Zhang H, Rutkowska A, Gonzalez-Martin A, Mirza M, Monk B, Vergote I, et al.
Cancer Res Commun
. 2024 Dec;
5(1):178-186.
PMID: 39636225
The presented retrospective analysis suggests, to the best of our knowledge for the first time, a potential significant interaction between statins and niraparib in clinical settings. Nevertheless, further investigations are...
3.
Rutkowska A, Eberl H, Werner T, Hennrich M, Sevin D, Petretich M, et al.
Cancer Res Commun
. 2024 Jul;
4(9):2427-2443.
PMID: 39028932
Significance: The presented data indicate, to our knowledge, for the first time, the potential benefit of concomitant modulation of cholesterol biosynthesis pathway and PARP inhibition and highlight the need for...
4.
Burtscher M, Gade S, Garrido-Rodriguez M, Rutkowska A, Werner T, Eberl H, et al.
Mol Syst Biol
. 2024 Mar;
20(4):458-474.
PMID: 38454145
Complex disease phenotypes often span multiple molecular processes. Functional characterization of these processes can shed light on disease mechanisms and drug effects. Thermal Proteome Profiling (TPP) is a mass-spectrometry (MS)...
5.
Mateus A, Kurzawa N, Perrin J, Bergamini G, Savitski M
Annu Rev Pharmacol Toxicol
. 2021 Sep;
62:465-482.
PMID: 34499524
Drug target deconvolution can accelerate the drug discovery process by identifying a drug's targets (facilitating medicinal chemistry efforts) and off-targets (anticipating toxicity effects or adverse drug reactions). Multiple mass spectrometry-based...
6.
Thomson D, Bergamini G
Expert Opin Ther Pat
. 2021 Mar;
31(9):785-794.
PMID: 33724136
: TANK-binding kinase 1 (TBK1) is a key mediator of innate immunity processes and studies have reported on its role in inflammatory and autoimmune diseases. Moreover, several studies have also...
7.
Echalier C, Rutkowska A, Kojic A, Thomson D, Edwards L, McKay B, et al.
Chem Commun (Camb)
. 2021 Jan;
57(14):1814-1817.
PMID: 33480895
Click chemistry probes have improved the study of drug interactions in live cells and relevant disease models. Proper design of the probes, including the choice of the click moiety coupled...
8.
Khan M, Poeckel D, Halavatyi A, Zukowska-Kasprzyk J, Stein F, Vappiani J, et al.
Eur Respir J
. 2020 Dec;
58(1).
PMID: 33361096
Fibrosis can affect any organ, resulting in the loss of tissue architecture and function with often life-threatening consequences. Pathologically, fibrosis is characterised by the expansion of connective tissue due to...
9.
Ortiz-Meoz R, Wang L, Matico R, Rutkowska-Klute A, De la Rosa M, Bedard S, et al.
Chembiochem
. 2020 Sep;
22(3):516-522.
PMID: 32974990
Indoleamine-2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme that catalyzes the rate-limiting step in the kynurenine pathway of tryptophan (TRP) metabolism. As it is an inflammation-induced immunoregulatory enzyme, pharmacological inhibition of...
10.
Woodcock H, Eley J, Guillotin D, Plate M, Nanthakumar C, Martufi M, et al.
Nat Commun
. 2020 Sep;
11(1):4680.
PMID: 32917879
An amendment to this paper has been published and can be accessed via a link at the top of the paper.