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Giorgos Hiotis

Explore the profile of Giorgos Hiotis including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 18
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Recent Articles
1.
Yang S, Hiotis G, Wang Y, Chen J, Wang J, Kim M, et al.
Nat Commun . 2022 Oct; 13(1):6393. PMID: 36302771
Vaccines targeting HIV-1's gp160 spike protein are stymied by high viral mutation rates and structural chicanery. gp160's membrane-proximal external region (MPER) is the target of naturally arising broadly neutralizing antibodies...
2.
Hsiao J, Neugroschl A, Chui A, Taabazuing C, Griswold A, Wang Q, et al.
J Biol Chem . 2022 May; 298(7):102032. PMID: 35580636
CARD8 is a pattern-recognition receptor that forms a caspase-1-activating inflammasome. CARD8 undergoes constitutive autoproteolysis, generating an N-terminal (NT) fragment with a disordered region and a ZU5 domain and a C-terminal...
3.
Hyland C, Mfarej M, Hiotis G, Lancaster S, Novak N, Iovine M, et al.
Mol Biol Cell . 2021 Aug; 32(20):ar13. PMID: 34379446
Gap junctions mediate direct cell-to-cell communication by forming channels that physically couple cells, thereby linking their cytoplasm, permitting the exchange of molecules, ions, and electrical impulses. Gap junctions are assembled...