Gina Giase
Overview
Explore the profile of Gina Giase including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
125
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0
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Recent Articles
1.
Luo J, Li L, Niu M, Kong D, Jiang Y, Poudel S, et al.
Mol Psychiatry
. 2024 May;
29(11):3330-3343.
PMID: 38724566
Psychiatric disorders are highly heritable yet polygenic, potentially involving hundreds of risk genes. Genome-wide association studies have identified hundreds of genomic susceptibility loci with susceptibility to psychiatric disorders; however, the...
2.
Liang Q, Jiang Y, Shieh A, Zhou D, Chen R, Wang F, et al.
bioRxiv
. 2023 Oct;
PMID: 37873195
Background: The impact of genetic variants on gene expression has been intensely studied at the transcription level, yielding in valuable insights into the association between genes and the risk of...
3.
Bradley H, Fine D, Minai Y, Gilabert L, Gregory K, Smith L, et al.
Pediatr Res
. 2023 Jul;
94(6):2098-2104.
PMID: 37500757
Background: Maternal stress has negative consequences on infant behavioral development, and COVID-19 presented uniquely stressful situations to mothers of infants born during the pandemic. We hypothesized that mothers with higher...
4.
Li Z, Min S, Alliey-Rodriguez N, Giase G, Cheng L, Craig D, et al.
Neurobiol Aging
. 2023 Jan;
123:222-232.
PMID: 36599749
Accumulation of somatic mutations in human neurons is associated with aging and neurodegeneration. To shed light on the somatic mutational burden in Alzheimer's disease (AD) neurons and get more insight...
5.
Hu M, Xia Y, Zong X, Sweeney J, Bishop J, Liao Y, et al.
Psychiatry Res
. 2022 Sep;
317:114789.
PMID: 36075150
Background: Second generation antipsychotics such as risperidone are first-line pharmacotherapy treatment choices for schizophrenia. However, our ability to reliably predict and monitor treatment reaction is impeded by the lack of...
6.
MacNeill L, Krogh-Jespersen S, Zhang Y, Giase G, Edwards R, Petitclerc A, et al.
Infancy
. 2022 Sep;
28(1):136-157.
PMID: 36070207
The association between prenatal stress and children's socioemotional development is well established. The COVID-19 pandemic has been a particularly stressful period, which may impact the gestational environment. However, most studies...
7.
Min S, Li Z, Shieh A, Giase G, Bao R, Zhang C, et al.
Neurobiol Aging
. 2021 Aug;
108:207-209.
PMID: 34392980
Somatic mutations arise randomly or are induced by environmental factors, which may increase the risk of Alzheimer's disease (AD). Identifying somatic mutations in sporadic AD (SAD) may provide new insight...
8.
Jiang Y, Giase G, Grennan K, Shieh A, Xia Y, Han L, et al.
PLoS Comput Biol
. 2020 Apr;
16(4):e1007522.
PMID: 32282793
Studies of complex disorders benefit from integrative analyses of multiple omics data. Yet, sample mix-ups frequently occur in multi-omics studies, weakening statistical power and risking false findings. Accurately aligning sample...
9.
Xia Y, Dai R, Wang K, Jiao C, Zhang C, Xu Y, et al.
Mol Psychiatry
. 2019 Apr;
26(3):835-848.
PMID: 30976086
Many psychiatric disorders are characterized by a strong sex difference, but the mechanisms behind sex-bias are not fully understood. DNA methylation plays important roles in regulating gene expression, ultimately impacting...
10.
Chen C, Meng Q, Xia Y, Ding C, Wang L, Dai R, et al.
Sci Transl Med
. 2018 Dec;
10(472).
PMID: 30545964
Schizophrenia and bipolar disorder are complex psychiatric diseases with risks contributed by multiple genes. Dysregulation of gene expression has been implicated in these disorders, but little is known about such...