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Gilles Favre

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Articles 112
Citations 2171
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Recent Articles
1.
Hurtado M, Khajavi L, Essabbar A, Kammer M, Xie T, Coullomb A, et al.
Front Immunol . 2024 Nov; 15:1394965. PMID: 39606240
Background: Lung cancer is the leading cause of cancer death worldwide, with poor survival despite recent therapeutic advances. A better understanding of the complexity of the tumor microenvironment is needed...
2.
Figarol S, Delahaye C, Gence R, Doussine A, Cerapio J, Brachais M, et al.
Nat Commun . 2024 Jun; 15(1):5345. PMID: 38937474
Drug-tolerance has emerged as one of the major non-genetic adaptive processes driving resistance to targeted therapy (TT) in non-small cell lung cancer (NSCLC). However, the kinetics and sequence of molecular...
3.
Geraud M, Cristini A, Salimbeni S, Bery N, Jouffret V, Russo M, et al.
Cell Rep . 2024 May; 43(5):114214. PMID: 38761375
TDP1 removes transcription-blocking topoisomerase I cleavage complexes (TOP1ccs), and its inactivating H493R mutation causes the neurodegenerative syndrome SCAN1. However, the molecular mechanism underlying the SCAN1 phenotype is unclear. Here, we...
4.
Castillo S, Gence R, Pagan D, Koraichi F, Bouchenot C, Pons B, et al.
Eur J Cell Biol . 2023 Aug; 102(4):151355. PMID: 37639782
Small GTPases are highly regulated proteins that control essential signaling pathways through the activity of their effector proteins. Among the RHOA subfamily, RHOB regulates peculiar functions that could be associated...
5.
Boutonnet A, Pradines A, Mano M, Kreczman-Brun M, Mazieres J, Favre G, et al.
Anal Chem . 2023 Jun; 95(24):9263-9270. PMID: 37279458
Cell-free DNA in human blood plasma (cfDNA) is now widely used and studied as a biomarker for several physiological and pathological situations. In addition to genetic and epigenetic alterations that...
6.
Mascarau R, Woottum M, Fromont L, Gence R, Cantaloube-Ferrieu V, Vahlas Z, et al.
J Cell Biol . 2023 Mar; 222(5). PMID: 36988579
Macrophages are essential for HIV-1 pathogenesis and represent major viral reservoirs. Therefore, it is critical to understand macrophage infection, especially in tissue macrophages, which are widely infected in vivo, but...
7.
Carrier A, Desjobert C, Lobjois V, Rigal L, Busato F, Tost J, et al.
Clin Epigenetics . 2022 Nov; 14(1):156. PMID: 36443814
The protocadherin proteins are cell adhesion molecules at the crossroad of signaling pathways playing a major role in neuronal development. It is now understood that their role as signaling hubs...
8.
Carrier A, Desjobert C, Ponger L, Lamant L, Bustos M, Torres-Ferreira J, et al.
Elife . 2022 Sep; 11. PMID: 36125262
Aberrant DNA methylation is a well-known feature of tumours and has been associated with metastatic melanoma. However, since melanoma cells are highly heterogeneous, it has been challenging to use affected...
9.
Keller L, Tardy C, Ligat L, Le Pennec S, Bery N, Koraichi F, et al.
Front Immunol . 2022 Sep; 13:980539. PMID: 36059552
Strategies based on intracellular expression of artificial binding domains present several advantages over manipulating nucleic acid expression or the use of small molecule inhibitors. Intracellularly-functional nanobodies can be considered as...
10.
Delahaye C, Figarol S, Pradines A, Favre G, Mazieres J, Calvayrac O
Cancers (Basel) . 2022 Jun; 14(11). PMID: 35681591
Lung cancer is the leading cause of cancer-related deaths among men and women worldwide. Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are effective therapies for advanced non-small-cell lung cancer (NSCLC)...