Giel Hendriks
Overview
Explore the profile of Giel Hendriks including associated specialties, affiliations and a list of published articles.
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50
Citations
932
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Recent Articles
1.
Ter Braak B, Loonstra-Wolters L, Elbertse K, Osterlund T, Hendriks G, Jamalpoor A
Toxicology
. 2024 Oct;
509:153970.
PMID: 39396605
In vitro chemical safety assessment often relies on simple and general cytotoxicity endpoint measurements and fails to adequately predict human toxicity. To improve the in vitro chemical safety assessment, it...
2.
Hendriks G, Adriaens E, Allemang A, Clements J, Cole G, Derr R, et al.
Environ Mol Mutagen
. 2024 Mar;
65(1-2):4-24.
PMID: 38545858
ToxTracker is a mammalian cell reporter assay that predicts the genotoxic properties of compounds with high accuracy. By evaluating induction of various reporter genes that play a key role in...
3.
Moreau M, Jamalpoor A, Hall J, Fisher J, Hartvelt S, Hendriks G, et al.
Toxicology
. 2023 Nov;
500:153684.
PMID: 38029956
in vitro screening platforms to assess teratogenic potential of compounds are emerging rapidly. ReproTracker is a human induced pluripotent stem cells (hiPSCs)-based biomarker assay that is shown to identify the...
4.
Demarta-Gatsi C, Jamalpoor A, Hendriks G, Tornesi B
Birth Defects Res
. 2023 May;
115(12):1105-1108.
PMID: 37219047
No abstract available.
5.
Thakkar Y, Moustakas H, Moelijker N, Hendriks G, Brandsma I, Pfuhler S, et al.
Environ Mol Mutagen
. 2023 Feb;
64(4):234-243.
PMID: 36762970
To determine the utility of the ToxTracker assay in animal alternative testing strategies, the genotoxic potential of four fragrance materials (2-octen-4-one, lauric aldehyde, veratraldehyde, and p-methoxy cinnamaldehyde) were tested in...
6.
Boisvert L, Derr R, Osterlund T, Hendriks G, Brandsma I
Environ Mol Mutagen
. 2023 Jan;
64(2):132-143.
PMID: 36645179
ToxTracker is an in vitro mammalian stem cell-based reporter assay that detects activation of specific cellular signaling pathways (DNA damage, oxidative stress, and/or protein damage) upon chemical exposure using flow...
7.
Beal M, Audebert M, Barton-Maclaren T, Battaion H, Bemis J, Cao X, et al.
Environ Mol Mutagen
. 2022 Dec;
64(2):105-122.
PMID: 36495195
Genotoxicity assessment is a critical component in the development and evaluation of chemicals. Traditional genotoxicity assays (i.e., mutagenicity, clastogenicity, and aneugenicity) have been limited to dichotomous hazard classification, while other...
8.
Osimitz T, Droege W, Hendriks G, Blais M
J Toxicol Environ Health A
. 2022 Jun;
85(19):783-797.
PMID: 35702027
It has been reported that incorporation of fire retardants into home furnishings and electronics increases the toxicity of smoke produced during combustion in house fires. Studies have been limited to...
9.
Brandsma I, Derr R, Zhang G, Moelijker N, Hendriks G, Osterlund T
Toxicol Lett
. 2022 May;
362:50-58.
PMID: 35569722
Nucleoside analogues have long been designed and tested in cancer treatment and against viral infections. However, several early compounds were shown to have mutagenic properties as a consequence of their...
10.
Cho E, Allemang A, Audebert M, Chauhan V, Dertinger S, Hendriks G, et al.
Environ Mol Mutagen
. 2022 Mar;
63(3):118-134.
PMID: 35315142
The Genetic Toxicology Technical Committee (GTTC) of the Health and Environmental Sciences Institute (HESI) is developing adverse outcome pathways (AOPs) that describe modes of action leading to potentially heritable genomic...