Gianluca Matteoli
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Explore the profile of Gianluca Matteoli including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Ke B, Dragoni G, Matteoli G
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684719
Intestinal fibroblasts are pivotal players in maintaining tissue homeostasis and orchestrating responses to injury and inflammation within the gastrointestinal (GI) tract. Fibroblasts contribute significantly to the pathogenesis of inflammatory bowel...
2.
Jacobs I, Deleu S, Ke B, Cremer J, Dilissen E, De Hertogh G, et al.
Sci Rep
. 2024 Nov;
14(1):27133.
PMID: 39511371
Eosinophils were previously reported to play a role in intestinal inflammation and fibrosis. Whether this is as a bystander or as an active participant is still up for debate. Moreover,...
3.
Biscu F, Zouzaf A, Cicia D, Pridans C, Matteoli G
Eur J Immunol
. 2024 Sep;
54(12):e2451139.
PMID: 39308210
Macrophages are instrumental in maintaining tissue homeostasis, modulating inflammation, and driving regeneration. The advent of omics techniques has led to the identification of numerous tissue-specific macrophage subtypes, thereby introducing the...
4.
Covelli V, Buonocore M, Grimaldi M, Scrima M, Santoro A, Marino C, et al.
Eur J Med Chem
. 2024 Sep;
279:116871.
PMID: 39303514
Bone diseases are medical conditions caused by the loss of bone homeostasis consecutive to increased osteoclast activity and diminished osteoblast activity. The mevalonate pathway (MVA) is crucial for maintaining this...
5.
Deleu S, Jacobs I, Vazquez Castellanos J, Verstockt S, Trindade de Carvalho B, Subotic A, et al.
Nutrients
. 2024 Aug;
16(16).
PMID: 39203805
Acetate-producing var. strains could exert improved effects on ulcerative colitis, which here, was preclinically evaluated in an acute dextran sodium sulphate induced model of colitis. Nine-week-old female mice were divided...
6.
Dragoni G, Ke B, Picariello L, Abdurahiman S, Ceni E, Biscu F, et al.
J Crohns Colitis
. 2024 Aug;
19(1.
PMID: 39126198
Background And Aims: During early phases of inflammation, activated neutrophils extrude neutrophil extracellular traps (NETs) in a peptidyl arginine deiminase 4 (PAD4)-dependent manner, aggravating tissue injury and remodeling. In this...
7.
Ke B, Abdurahiman S, Biscu F, Zanella G, Dragoni G, Santhosh S, et al.
J Clin Invest
. 2024 Jul;
134(16).
PMID: 39042469
Crohn's disease (CD) is marked by recurring intestinal inflammation and tissue injury, often resulting in fibrostenosis and bowel obstruction, necessitating surgical intervention with high recurrence rates. To elucidate the mechanisms...
8.
van Baarle L, De Simone V, Schneider L, Santhosh S, Abdurahiman S, Biscu F, et al.
Nat Commun
. 2024 Jul;
15(1):6079.
PMID: 39030280
Enteric glia have been recently recognized as key components of the colonic tumor microenvironment indicating their potential role in colorectal cancer pathogenesis. Although enteric glia modulate immune responses in other...
9.
Santhosh S, Zanoletti L, Stamp L, Hao M, Matteoli G
Front Immunol
. 2024 Jul;
15:1408744.
PMID: 38957473
Enteric glial cells (EGCs) are an essential component of the enteric nervous system (ENS) and play key roles in gastrointestinal development, homeostasis, and disease. Derived from neural crest cells, EGCs...
10.
Fibrostricturing Crohn's Disease Is Marked by an Increase in Active Eosinophils in the Deeper Layers
Jacobs I, Ke B, Ceulemans M, Cremer J, dHoore A, Bislenghi G, et al.
Clin Transl Gastroenterol
. 2024 May;
15(7):e00706.
PMID: 38690831
Introduction: Approximately 50% of patients with Crohn's disease (CD) develop intestinal strictures necessitating surgery. The immune cell distribution in these strictures remains uncharacterized. We aimed to identify the immune cells...