Giancarlo Ghiselli
Overview
Explore the profile of Giancarlo Ghiselli including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
152
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Maccarana M, Tykesson E, Pera E, Gouignard N, Fang J, Malmstrom A, et al.
Glycobiology
. 2021 Jun;
31(10):1319-1329.
PMID: 34192316
Mucopolysaccharidosis type I (MPS-I) is a rare lysosomal storage disorder caused by deficiency of the enzyme alpha-L-iduronidase, which removes iduronic acid in both chondroitin/dermatan sulfate (CS/DS) and heparan sulfate (HS)...
2.
Ghiselli G
Medicines (Basel)
. 2019 Aug;
6(3).
PMID: 31362364
The polyanionic nature and the ability to interact with proteins with different affinities are properties of sulfated glycosaminoglycans (GAGs) that determine their biological function. In designing drugs affecting the interaction...
3.
Ghiselli G
Med Res Rev
. 2016 Dec;
37(5):1051-1094.
PMID: 28029167
Glycosaminoglycans (GAGs) are a heterogeneous family of unbranched polysaccharides that exist in either a free state or attached to proteins and are found on the cell surface as well as...
4.
Ghiselli G, Maccarana M
Drug Discov Today
. 2016 May;
21(7):1162-9.
PMID: 27217160
Glycosaminoglycans (GAGs) are charged polysaccharides ubiquitously present at the cell surface and in the extracellular matrix. GAGs are crucial for cellular homeostasis, and their metabolism is altered during pathological processes....
5.
Long S, Stefani F, Biondi S, Ghiselli G, Panunzio M
Bioorg Med Chem
. 2013 Aug;
21(18):5811-22.
PMID: 23910991
The enzyme α-glucosidase has attracted interest owing to its involvement in the digestive process of carbohydrate, its role in intracellular glycoprotein trafficking, tumorigenesis and viral infection. In this study, several...
6.
Bartolini B, Thelin M, Svensson L, Ghiselli G, van Kuppevelt T, Malmstrom A, et al.
PLoS One
. 2013 Jul;
8(7):e66704.
PMID: 23843960
Aortic smooth muscle cells produce chondroitin/dermatan sulfate (CS/DS) proteoglycans that regulate extracellular matrix organization and cell behavior in normal and pathological conditions. A unique feature of CS/DS proteoglycans is the...
7.
SMC3 knockdown triggers genomic instability and p53-dependent apoptosis in human and zebrafish cells
Ghiselli G
Mol Cancer
. 2006 Nov;
5:52.
PMID: 17081288
Background: The structural maintenance of chromosome 3 (SMC3) protein is a constituent of a number of nuclear multimeric protein complexes that are involved in DNA recombination and repair in addition...
8.
Ghiselli G, Liu C
Mol Cancer
. 2005 Sep;
4:34.
PMID: 16156898
Background: The Structural Maintenance of Chromosome 3 protein (SMC3) plays an essential role during the sister chromatid separation, is involved in DNA repair and recombination and participates in microtubule-mediated intracellular...
9.
Ghiselli G, Farber S
BMC Dev Biol
. 2005 Sep;
5:19.
PMID: 16156897
Background: Heparan sulfate (HS) is an ubiquitous component of the extracellular matrix that binds and modulates the activity of growth factors, cytokines and proteases. Animals with defective HS biosynthesis display...
10.
Ghiselli G, Agrawal A
Biochem J
. 2005 Apr;
390(Pt 2):493-9.
PMID: 15853773
Heparan sulphate (HS) is a ubiquitous constituent of the extracellular matrix that is required for the biological activity of circulating soluble and insoluble extracellular ligands. GLCE (D-glucuronyl C5-epimerase), an enzyme...