Germana Zaccagnini
Overview
Explore the profile of Germana Zaccagnini including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
908
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Recent Articles
1.
Izzo M, Battistini J, Golini E, Voellenkle C, Provenzano C, Orsini T, et al.
Clin Transl Med
. 2025 Feb;
15(2):e70227.
PMID: 39956955
Background: Myotonic dystrophy type 1 (DM1) is a genetic multisystemic disease, characterised by pleiotropic symptoms that exhibit notable variability in severity, nature and age of onset. The genetic cause of...
2.
Collado A, Jiao T, Kontidou E, Carvalho L, Chernogubova E, Yang J, et al.
Br J Pharmacol
. 2024 Oct;
182(2):417-431.
PMID: 39402703
Background And Purpose: MicroRNA (miR)-210 function in endothelial cells and its role in diabetes-associated endothelial dysfunction are not fully understood. We aimed to characterize the miR-210 function in endothelial cells...
3.
Colaianni D, Virga F, Tisi A, Stefanelli C, Zaccagnini G, Cusumano P, et al.
Biol Direct
. 2024 Oct;
19(1):90.
PMID: 39394614
Background: miR-210 is one of the most evolutionarily conserved microRNAs. It is known to be involved in several physiological and pathological processes, including response to hypoxia, angiogenesis, cardiovascular diseases and...
4.
Garoffolo G, Casaburo M, Amadeo F, Salvi M, Bernava G, Piacentini L, et al.
Circ Res
. 2022 Jun;
131(3):239-257.
PMID: 35770662
Background: Conversion of cardiac stromal cells into myofibroblasts is typically associated with hypoxia conditions, metabolic insults, and/or inflammation, all of which are predisposing factors to cardiac fibrosis and heart failure....
5.
Zaccagnini G, Greco S, Voellenkle C, Gaetano C, Martelli F
Antioxid Redox Signal
. 2021 Sep;
36(10-12):685-706.
PMID: 34521246
microRNA-210 (miR-210) is the master hypoxia-inducible miRNA (hypoxamiR) since it has been found to be significantly upregulated under hypoxia in a wide range of cell types. Gene ontology analysis of...
6.
Zaccagnini G, Greco S, Longo M, Maimone B, Voellenkle C, Fuschi P, et al.
Cell Death Dis
. 2021 May;
12(6):507.
PMID: 34006827
No abstract available.
7.
Zaccagnini G, Greco S, Longo M, Maimone B, Voellenkle C, Fuschi P, et al.
Cell Death Dis
. 2021 May;
12(5):435.
PMID: 33934122
Hypoxia-induced miR-210 is a crucial component of the tissue response to ischemia, stimulating angiogenesis and improving tissue regeneration. Previous analysis of miR-210 impact on the transcriptome in a mouse model...
8.
Zaccagnini G, Maimone B, Fuschi P, Longo M, da Silva D, Carrara M, et al.
Int J Mol Sci
. 2019 Dec;
21(1).
PMID: 31878120
Critical limb ischemia is the most serious form of peripheral artery disease, characterized by severe functional consequences, difficult clinical management and reduced life expectancy. The goal of this study was...
9.
Savoia M, Cencioni C, Mori M, Atlante S, Zaccagnini G, Devanna P, et al.
FASEB J
. 2018 Dec;
33(3):4107-4123.
PMID: 30526058
The epigenetic enzyme p300/CBP-associated factor (PCAF) belongs to the GCN5-related N-acetyltransferase (GNAT) family together with GCN5. Although its transcriptional and post-translational function is well characterized, little is known about its...
10.
Besnier M, Gasparino S, Vono R, Sangalli E, Facoetti A, Bollati V, et al.
Mol Ther
. 2018 Jun;
26(7):1694-1705.
PMID: 29908843
Therapies based on circulating proangiogenic cells (PACs) have shown promise in ischemic disease models but require further optimization to reach the bedside. Ischemia-associated hypoxia robustly increases microRNA-210 (miR-210) expression in...