Gerhard Blum
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Explore the profile of Gerhard Blum including associated specialties, affiliations and a list of published articles.
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10
Citations
169
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Recent Articles
1.
Blatzer M, Jukic E, Posch W, Schopf B, Binder U, Steger M, et al.
Antioxid Redox Signal
. 2015 Jun;
23(18):1424-38.
PMID: 26054424
Aims: Invasive fungal infections have significantly increased over the past decades in immunocompromised individuals and high-risk patients. Amphotericin B (AmB) exerts a powerful and broad activity against a vast array...
2.
Blatzer M, Blum G, Jukic E, Posch W, Gruber P, Nagl M, et al.
Antimicrob Agents Chemother
. 2015 Apr;
59(7):3778-88.
PMID: 25870060
The polyene antifungal amphotericin B (AmB) is widely used to treat life-threatening fungal infections. Even though AmB resistance is exceptionally rare in fungi, most Aspergillus terreus isolates exhibit an intrinsic...
3.
Rambach G, Blum G, Latge J, Fontaine T, Heinekamp T, Hagleitner M, et al.
J Infect Dis
. 2015 Mar;
212(7):1140-9.
PMID: 25810442
Background: Platelets were recently identified as a part of innate immunity. They are activated by contact with Aspergillus fumigatus; putative consequences include antifungal defense but also thrombosis, excessive inflammation, and...
4.
Mutschlechner W, Grif K, Blum G, Lass-Florl C
Med Mycol
. 2013 Jun;
51(8):876-9.
PMID: 23758105
We compared two PCR methods for molecular typing the medically important filamentous fungus Aspergillus terreus. In a set of 46 strains investigated we found 19 and 12 different fingerprinting types...
5.
Speth C, Blum G, Hagleitner M, Hortnagl C, Pfaller K, Posch B, et al.
Med Microbiol Immunol
. 2013 Jun;
202(5):379-89.
PMID: 23722593
Aspergillus terreus-induced invasive infections exhibit high lethality, partly due to the intrinsic resistance for amphotericin B (AmB). We compared the virulence and pathogenesis of an AmB-resistant isolate of A. terreus...
6.
Blum G, Hortnagl C, Jukic E, Erbeznik T, Pumpel T, Dietrich H, et al.
Antimicrob Agents Chemother
. 2013 Jan;
57(4):1583-8.
PMID: 23318794
Amphotericin B (AMB) is the predominant antifungal drug, but the mechanism of resistance is not well understood. We compared the in vivo virulence of an AMB-resistant Aspergillus terreus (ATR) isolate...
7.
Schmalreck A, Willinger B, Czaika V, Fegeler W, Becker K, Blum G, et al.
Mycopathologia
. 2012 Aug;
174(5-6):467-74.
PMID: 22864604
In vitro susceptibility testing of clinically important fungi becomes more and more essential due to the rising number of fungal infections in patients with impaired immune system. Existing standardized microbroth...
8.
Blum G, Eschertzhuber S, Auberger J, Ulmer H, Geltner C, Gastl G, et al.
Mycoses
. 2011 Jul;
55(3):237-43.
PMID: 21797937
The aim of this study was to investigate the relationship between fungal exposure prior to hospitalisation and ensuing onset of invasive mould infections (IMI) in patients at risk. Patients admitted...
9.
Blum G, Perkhofer S, Haas H, Schrettl M, Wurzner R, Dierich M, et al.
Antimicrob Agents Chemother
. 2008 Feb;
52(4):1553-5.
PMID: 18268082
This study investigated the basis for intrinsic amphotericin B (AMB) resistance in Aspergillus terreus. The ergosterol content, cell wall composition, and lipid peroxidation level had no influence on AMB resistance....
10.
Perkhofer S, Niederegger H, Blum G, Burgstaller W, Ledochowski M, Dierich M, et al.
Int J Antimicrob Agents
. 2007 Feb;
29(4):424-9.
PMID: 17276041
This study examined the direct interaction of serotonin (5-hydroxytryptamine (5-HT)) with Aspergillus species. Accumulation of 5-HT in aspergilli was investigated by immunofluorescence staining and laser confocal scanning microscopy. The influence...