Caroline Hortnagl
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Explore the profile of Caroline Hortnagl including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
194
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0
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Recent Articles
1.
Welte R, Oberacher H, Gasperetti T, Pfisterer H, Griesmacher A, Santner T, et al.
Antimicrob Agents Chemother
. 2021 May;
65(7):e0256520.
PMID: 33972242
The pharmacokinetics and antifungal activity of the echinocandins anidulafungin (AFG), micafungin (MFG), and caspofungin (CAS) were assessed in ascites fluid and plasma of critically ill adults treated for suspected or...
2.
Binder U, Arastehfar A, Schnegg L, Hortnagl C, Hilmioglu-Polat S, Perlin D, et al.
J Fungi (Basel)
. 2020 Dec;
6(4).
PMID: 33353200
While being the third leading cause of candidemia worldwide, numerous studies have shown severe clonal outbreaks due to fluconazole-resistant (FLCR) isolates associated with fluconazole therapeutic failure (FTF) with enhanced mortality....
3.
Megri Y, Arastehfar A, Boekhout T, Daneshnia F, Hortnagl C, Sartori B, et al.
Antimicrob Resist Infect Control
. 2020 Apr;
9(1):50.
PMID: 32264966
Background: Despite being associated with a high mortality and economic burden, data regarding candidemia are scant in Algeria. The aim of this study was to unveil the epidemiology of candidemia...
4.
Binder U, Aigner M, Risslegger B, Hortnagl C, Lass-Florl C, Lackner M
J Fungi (Basel)
. 2019 Sep;
5(3).
PMID: 31487830
Antifungal susceptibility testing (AFST) of clinical isolates is a tool in routine diagnostics to facilitate decision making on optimal antifungal therapy. The minimal inhibitory concentration (MIC)-phenomena (trailing and paradoxical effects...
5.
Maurer E, Hortnagl C, Lackner M, Grassle D, Naschberger V, Moser P, et al.
Med Mycol
. 2018 Jun;
57(3):351-362.
PMID: 29924357
Mucorales can cause cutaneous to deep-seated infections, mainly in the immunocompromised host, resulting in high mortality rates due to late and inefficient treatment. In this study, Galleria mellonella larvae were...
6.
Speth C, Blum G, Hagleitner M, Hortnagl C, Pfaller K, Posch B, et al.
Med Microbiol Immunol
. 2013 Jun;
202(5):379-89.
PMID: 23722593
Aspergillus terreus-induced invasive infections exhibit high lethality, partly due to the intrinsic resistance for amphotericin B (AmB). We compared the virulence and pathogenesis of an AmB-resistant isolate of A. terreus...
7.
Blum G, Hortnagl C, Jukic E, Erbeznik T, Pumpel T, Dietrich H, et al.
Antimicrob Agents Chemother
. 2013 Jan;
57(4):1583-8.
PMID: 23318794
Amphotericin B (AMB) is the predominant antifungal drug, but the mechanism of resistance is not well understood. We compared the in vivo virulence of an AMB-resistant Aspergillus terreus (ATR) isolate...
8.
Petrik M, Franssen G, Haas H, Laverman P, Hortnagl C, Schrettl M, et al.
Eur J Nucl Med Mol Imaging
. 2012 Apr;
39(7):1175-83.
PMID: 22526953
Purpose: Invasive pulmonary aspergillosis is mainly caused by Aspergillus fumigatus, and is one of the major causes of morbidity and mortality in immunocompromised patients. The mortality associated with invasive pulmonary...