Gerardo Pepe
Overview
Explore the profile of Gerardo Pepe including associated specialties, affiliations and a list of published articles.
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14
Citations
83
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Recent Articles
1.
Ballesio F, Pepe G, Ausiello G, Novelletto A, Helmer-Citterich M, Gherardini P
Noncoding RNA Res
. 2024 Jul;
9(4):1257-1270.
PMID: 39040814
We analyzed the structure of human long non-coding RNA (lncRNAs) genes to investigate whether the non-coding transcriptome is organized in modular domains, as is the case for protein-coding genes. To...
2.
Pepe G, Appierdo R, Ausiello G, Helmer-Citterich M, Gherardini P
Int J Mol Sci
. 2024 Apr;
25(8).
PMID: 38673810
Cardiovascular diseases (CVDs) represent a major concern for global health, whose mechanistic understanding is complicated by a complex interplay between genetic predisposition and environmental factors. Specifically, heart failure (HF), encompassing...
3.
Latini S, Venafra V, Massacci G, Bica V, Graziosi S, Pugliese G, et al.
Elife
. 2024 Apr;
12.
PMID: 38564252
Currently, the identification of patient-specific therapies in cancer is mainly informed by personalized genomic analysis. In the setting of acute myeloid leukemia (AML), patient-drug treatment matching fails in a subset...
4.
Latini A, Borgiani P, De Benedittis G, Ciccacci C, Novelli L, Pepe G, et al.
Gene
. 2024 Feb;
907:148279.
PMID: 38360126
The identification of rare genetic variants associated to Systemic Lupus Erythematosus (SLE) could also help to understand the pathogenic mechanisms at the basis of the disease. In this study we...
5.
Marchionni E, DApice M, Lupo V, Lattanzi G, Mattioli E, Lisignoli G, et al.
Bone Rep
. 2023 Dec;
19:101728.
PMID: 38076483
gene encodes the alpha-1 chain of type-II procollagen. Heterozygous pathogenic variants are associated with the broad clinical spectrum of genetic diseases known as type-II collagenopathies. We aimed to characterize the...
6.
Pericoli G, Galardi A, Paolini A, Petrilli L, Pepe G, Palma A, et al.
Cell Biosci
. 2023 Nov;
13(1):207.
PMID: 37957701
Background: Paediatric-type diffuse High-Grade Gliomas (PDHGG) are highly heterogeneous tumours which include distinct cell sub-populations co-existing within the same tumour mass. We have previously shown that primary patient-derived and optical...
7.
Cirotti C, Taddei I, Contadini C, Di Girolamo C, Pepe G, De Bardi M, et al.
Life Sci Alliance
. 2023 Oct;
7(1).
PMID: 37879937
Glioblastoma is a severe brain tumor characterized by an extremely poor survival rate of patients. Glioblastoma cancer cells escape to standard therapeutic protocols consisting of a combination of ionizing radiation...
8.
Ballarino M, Pepe G, Helmer-Citterich M, Palma A
Comput Struct Biotechnol J
. 2023 Oct;
21:4706-4716.
PMID: 37841333
In recent years, research on long non-coding RNAs (lncRNAs) has gained considerable attention due to the increasing number of newly identified transcripts. Several characteristics make their functional evaluation challenging, which...
9.
Olmi L, Pepe G, Helmer-Citterich M, Canini A, Gismondi A
Plant Foods Hum Nutr
. 2023 May;
78(2):399-406.
PMID: 37256506
Literature has proposed the existence of a cross kingdom regulation (CRK) between human and plants. In this context, microRNAs present in edible plants would be acquired through diet by the...
10.
Pepe G, Carrino C, Parca L, Helmer-Citterich M
Methods Mol Biol
. 2022 May;
2449:187-196.
PMID: 35507263
The prediction of the cancer cell lines sensitivity to a specific treatment is one of the current challenges in precision medicine. With omics and pharmacogenomics data being available for over...