Georges Martin
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Explore the profile of Georges Martin including associated specialties, affiliations and a list of published articles.
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26
Citations
1619
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Recent Articles
1.
Gaubert J, Mercier P, Martin G, Giovenazzo P, Derome N
Microorganisms
. 2024 Jun;
12(6).
PMID: 38930537
Against a backdrop of declining bee colony health, this study aims to gain a better understanding of the impact of an antimicrobial (Fumidil B, Can-Vet Animal Health Supplies Ltd., Guelph,...
2.
Ghosh S, Ataman M, Bak M, Borsch A, Schmidt A, Buczak K, et al.
Nucleic Acids Res
. 2022 Mar;
50(6):3096-3114.
PMID: 35234914
The mammalian cleavage factor I (CFIm) has been implicated in alternative polyadenylation (APA) in a broad range of contexts, from cancers to learning deficits and parasite infections. To determine how...
3.
Gruber A, Schmidt R, Ghosh S, Martin G, Gruber A, van Nimwegen E, et al.
Genome Biol
. 2018 Mar;
19(1):44.
PMID: 29592812
3' Untranslated regions (3' UTRs) length is regulated in relation to cellular state. To uncover key regulators of poly(A) site use in specific conditions, we have developed PAQR, a method...
4.
Martin G, Schmidt R, Gruber A, Ghosh S, Keller W, Zavolan M
J Vis Exp
. 2017 Oct;
(128).
PMID: 29053696
Studies in the last decade have revealed a complex and dynamic variety of pre-mRNA cleavage and polyadenylation reactions. mRNAs with long 3' untranslated regions (UTRs) are generated in differentiated cells...
5.
Gumienny R, Jedlinski D, Schmidt A, Gypas F, Martin G, Vina-Vilaseca A, et al.
Nucleic Acids Res
. 2016 Dec;
45(5):2341-2353.
PMID: 28031372
High-throughput sequencing has greatly facilitated the discovery of long and short non-coding RNAs (ncRNAs), which frequently guide ribonucleoprotein complexes to RNA targets, to modulate their metabolism and expression. However, for...
6.
Gruber A, Schmidt R, Gruber A, Martin G, Ghosh S, Belmadani M, et al.
Genome Res
. 2016 Jul;
26(8):1145-59.
PMID: 27382025
Alternative polyadenylation (APA) is a general mechanism of transcript diversification in mammals, which has been recently linked to proliferative states and cancer. Different 3' untranslated region (3' UTR) isoforms interact...
7.
8.
Kanitz A, Gypas F, Gruber A, Gruber A, Martin G, Zavolan M
Genome Biol
. 2015 Jul;
16:150.
PMID: 26201343
Background: Understanding the regulation of gene expression, including transcription start site usage, alternative splicing, and polyadenylation, requires accurate quantification of expression levels down to the level of individual transcript isoforms....
9.
Gruber A, Martin G, Muller P, Schmidt A, Gruber A, Gumienny R, et al.
Nat Commun
. 2014 Nov;
5:5465.
PMID: 25413384
Alternative polyadenylation is a cellular mechanism that generates mRNA isoforms differing in their 3' untranslated regions (3' UTRs). Changes in polyadenylation site usage have been described upon induction of proliferation...
10.
Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33
Schonemann L, Kuhn U, Martin G, Schafer P, Gruber A, Keller W, et al.
Genes Dev
. 2014 Oct;
28(21):2381-93.
PMID: 25301781
Cleavage and polyadenylation specificity factor (CPSF) is the central component of the 3' processing machinery for polyadenylated mRNAs in metazoans: CPSF recognizes the polyadenylation signal AAUAAA, providing sequence specificity in...