George Tzortzis
Overview
Explore the profile of George Tzortzis including associated specialties, affiliations and a list of published articles.
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36
Citations
1408
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Recent Articles
11.
Savignac H, Couch Y, Stratford M, Bannerman D, Tzortzis G, Anthony D, et al.
Brain Behav Immun
. 2015 Oct;
52:120-131.
PMID: 26476141
The manipulation of the enteric microbiota with specific prebiotics and probiotics, has been shown to reduce the host's inflammatory response, alter brain chemistry, and modulate anxiety behaviour in both rodents...
12.
Vulevic J, Juric A, Walton G, Claus S, Tzortzis G, Toward R, et al.
Br J Nutr
. 2015 Jul;
114(4):586-95.
PMID: 26218845
It is recognised that ageing induces various changes to the human colonic microbiota. Most relevant is a reduction in bifidobacteria, which is a health-positive genus. Prebiotics, such as galacto-oligosaccharides (GOS),...
13.
Costabile A, Walton G, Tzortzis G, Vulevic J, Charalampopoulos D, Gibson G
Gut Microbes
. 2015 Jun;
6(5):300-9.
PMID: 26099034
Prebiotics are dietary carbohydrates that favourably modulate the gut microbiota. The aims of the present study were to develop a functional prebiotic bread using Bimuno®, (galactooligosaccharide (B-GOS) mixture), for modulation...
14.
Costabile A, Walton G, Tzortzis G, Vulevic J, Charalampopoulos D, Gibson G
PLoS One
. 2015 Mar;
10(3):e0121955.
PMID: 25807417
A three-stage continuous fermentative colonic model system was used to monitor in vitro the effect of different orange juice formulations on prebiotic activity. Three different juices with and without Bimuno,...
15.
Schmidt K, Cowen P, Harmer C, Tzortzis G, Errington S, Burnet P
Psychopharmacology (Berl)
. 2014 Dec;
232(10):1793-801.
PMID: 25449699
Rationale: There is now compelling evidence for a link between enteric microbiota and brain function. The ingestion of probiotics modulates the processing of information that is strongly linked to anxiety...
16.
Cook M, Tzortzis G, Charalampopoulos D, Khutoryanskiy V
Int J Pharm
. 2014 Mar;
466(1-2):400-8.
PMID: 24657143
Probiotic bacteria have gained popularity as a defence against disorders of the bowel. However, the acid sensitivity of these cells results in a loss of viability during gastric passage and,...
17.
Savignac H, Corona G, Mills H, Chen L, Spencer J, Tzortzis G, et al.
Neurochem Int
. 2013 Oct;
63(8):756-64.
PMID: 24140431
The influence of the gut microbiota on brain chemistry has been convincingly demonstrated in rodents. In the absence of gut bacteria, the central expression of brain derived neurotropic factor, (BDNF),...
18.
Osman A, Tzortzis G, Rastall R, Charalampopoulos D
J Agric Food Chem
. 2013 Feb;
61(9):2213-23.
PMID: 23383752
The bifidobacterial β-galactosidase (BbgIV) was produced in E. coli DH5α at 37 and 30 °C in a 5 L bioreactor under varied conditions of dissolved oxygen (dO2) and pH. The...
19.
Vulevic J, Juric A, Tzortzis G, Gibson G
J Nutr
. 2013 Jan;
143(3):324-31.
PMID: 23303873
Metabolic syndrome is a set of disorders that increases the risk of developing cardiovascular disease. The gut microbiota is altered toward a less beneficial composition in overweight adults and this...
20.
Cook M, Saratoon T, Tzortzis G, Edwards A, Charalampopoulos D, Khutoryanskiy V
Biomacromolecules
. 2013 Jan;
14(2):387-93.
PMID: 23301617
If acid-sensitive drugs or cells are administered orally, there is often a reduction in efficacy associated with gastric passage. Formulation into a polymer matrix is a potential method to improve...