George Maiti
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Explore the profile of George Maiti including associated specialties, affiliations and a list of published articles.
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15
Citations
183
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Recent Articles
1.
Wang Y, Li W, McDermott M, Son G, Maiti G, Zhou F, et al.
Sci Transl Med
. 2024 Dec;
16(778):eado4856.
PMID: 39693412
Sjögren's disease (SjD) is an autoimmune disorder characterized by progressive salivary and lacrimal gland dysfunction, inflammation, and destruction, as well as extraglandular manifestations. SjD is associated with autoreactive B and...
2.
Ashworth S, Dhanuka M, Khodadadi-Jamayran A, Koduri M, Maiti G, Chakravarti S
Ocul Surf
. 2024 Nov;
35:68-80.
PMID: 39615587
Purpose: We developed human cornea organoids (HCOs) from induced pluripotent stem cells (iPSCs) where single-cell RNA-sequence (scRNA-seq) analysis suggested similarity with developing rather than mature human corneas. We performed immunohistology...
3.
Maiti G, Frikeche J, Loomis C, Chakravarti S
bioRxiv
. 2024 Nov;
PMID: 39484444
The extracellular matrix (ECM) is known to regulate innate immune cells but its role in T cell functions is poorly understood. Here, we show a protective role for ECM proteoglycans,...
4.
Wang Y, Li W, McDermott M, Son G, Maiti G, Zhou F, et al.
bioRxiv
. 2024 Feb;
PMID: 38328096
Objectives: Sjögren's Disease (SjD) is an autoimmune disorder characterized by progressive dysfunction, inflammation and destruction of salivary and lacrimal glands, and by extraglandular manifestations. Its etiology and pathophysiology remain incompletely...
5.
Choi T, Maiti G, Chakravarti S
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834438
Lumican is an extracellular matrix proteoglycan known to regulate toll-like receptor (TLR) signaling in innate immune cells. In experimental settings, lumican suppresses TLR9 signaling by binding to and sequestering its...
6.
Maiti G, Ashworth S, Choi T, Chakravarti S
Matrix Biol
. 2023 Oct;
123:48-58.
PMID: 37793508
In this review we highlight emerging immune regulatory functions of lumican, keratocan, fibromodulin, biglycan and decorin, which are members of the small leucine-rich proteoglycans (SLRP) of the extracellular matrix (ECM)....
7.
Choi T, Maiti G, Chakravarti S
bioRxiv
. 2023 Sep;
PMID: 37662233
Lumican is an extracellular matrix proteoglycan, known to regulate toll-like receptor (TLR) signaling in innate immune cells. In experimental settings, lumican suppresses TLR9 signaling by binding to, and sequestering its...
8.
Maiti G, Monteiro de Barros M, Hu N, Dolgalev I, Roshan M, Foster J, et al.
PNAS Nexus
. 2023 Jan;
1(5):pgac246.
PMID: 36712326
The cornea is a protective and refractive barrier in the eye crucial for vision. Understanding the human cornea in health, disease, and cell-based treatments can be greatly advanced with cornea...
9.
Maiti G, Frikeche J, Lam C, Biswas A, Shinde V, Samanovic M, et al.
Proc Natl Acad Sci U S A
. 2021 Jul;
118(27).
PMID: 34215697
Infections and inflammation are profoundly influenced by the extracellular matrix (ECM), but their molecular underpinnings are ill defined. Here, we demonstrate that lumican, an ECM protein normally associated with collagens,...
10.
Biswas A, Mandal R, Chakraborty S, Maiti G
Int Rev Immunol
. 2021 May;
41(4):448-463.
PMID: 33978550
The impact of SARS-CoV-2 and COVID-19 disease susceptibility varies depending on the age and health status of an individual. Currently, there are more than 140 COVID-19 vaccines under development. However,...