Yin-Hu Wang
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Explore the profile of Yin-Hu Wang including associated specialties, affiliations and a list of published articles.
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31
Citations
404
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Recent Articles
1.
Zhong L, Wang Y, Kahlfuss S, Jishage M, McDermott M, Yang J, et al.
Nat Immunol
. 2025 Feb;
26(3):484-496.
PMID: 39984734
Stromal interaction molecule 1 (STIM1) is critical for store-operated Ca entry (SOCE) and T cell activation. T helper 1 (T1) cells, which express T-bet (encoded by TBX21), mediate immunity to...
2.
Wang Y, Li W, McDermott M, Son G, Maiti G, Zhou F, et al.
Sci Transl Med
. 2024 Dec;
16(778):eado4856.
PMID: 39693412
Sjögren's disease (SjD) is an autoimmune disorder characterized by progressive salivary and lacrimal gland dysfunction, inflammation, and destruction, as well as extraglandular manifestations. SjD is associated with autoreactive B and...
3.
Wang Y, Li W, McDermott M, Son G, Maiti G, Zhou F, et al.
bioRxiv
. 2024 Feb;
PMID: 38328096
Objectives: Sjögren's Disease (SjD) is an autoimmune disorder characterized by progressive dysfunction, inflammation and destruction of salivary and lacrimal glands, and by extraglandular manifestations. Its etiology and pathophysiology remain incompletely...
4.
Zhu F, McMonigle R, Schroeder A, Xia X, Figge D, Greer B, et al.
Nat Commun
. 2023 Jun;
14(1):3611.
PMID: 37330549
Follicular helper T (Tfh) cells are essential for germinal center (GC) B cell responses. However, it is not clear which PD-1CXCR5Bcl6CD4 T cells will differentiate into PD-1CXCR5Bcl6 GC-Tfh cells and...
5.
Emrich S, Yoast R, Zhang X, Fike A, Wang Y, Bricker K, et al.
Elife
. 2023 Feb;
12.
PMID: 36803766
The essential role of store-operated Ca entry (SOCE) through Ca release-activated Ca (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE...
6.
Wang Y, Noyer L, Kahlfuss S, Raphael D, Tao A, Kaufmann U, et al.
Sci Adv
. 2022 Oct;
8(40):eabn6552.
PMID: 36206339
T cell activation and function depend on Ca signals mediated by store-operated Ca entry (SOCE) through Ca release-activated Ca (CRAC) channels formed by ORAI1 proteins. We here investigated how SOCE...
7.
Letizia M, Wang Y, Kaufmann U, Gerbeth L, Sand A, Brunkhorst M, et al.
EMBO Mol Med
. 2022 Aug;
14(9):e15687.
PMID: 35919953
Inflammatory bowel disease (IBD) is characterized by dysregulated intestinal immune responses. Using mass cytometry (CyTOF) to analyze the immune cell composition in the lamina propria (LP) of patients with ulcerative...
8.
Wang L, Noyer L, Wang Y, Tao A, Li W, Zhu J, et al.
J Gen Physiol
. 2022 Jul;
154(10).
PMID: 35861698
Ca2+ signals regulate the function of many immune cells and promote immune responses to infection, cancer, and autoantigens. Ca2+ influx in immune cells is mediated by store-operated Ca2+ entry (SOCE)...
9.
Concepcion A, Wagner 2nd L, Zhu J, Tao A, Yang J, Khodadadi-Jamayran A, et al.
Nat Immunol
. 2022 Feb;
23(2):287-302.
PMID: 35105987
The volume-regulated anion channel (VRAC) is formed by LRRC8 proteins and is responsible for the regulatory volume decrease (RVD) after hypotonic cell swelling. Besides chloride, VRAC transports other molecules, for...
10.
Wang Y, Tao A, Feske S
Cell Calcium
. 2020 Jun;
90:102227.
PMID: 32563861
B lymphocytes are an important component of the adaptive and innate immune system because of their ability to secrete antibodies and to present antigens to T cells, which is critical...