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» Authors » George Haret-Richter

George Haret-Richter

Explore the profile of George Haret-Richter including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 146
Followers 0
Related Specialties
General Medicine
Microbiology
Science
Top 10 Co-Authors
Cristian Apetrei
Ivona Pandrea
Cuiling Xu
Jan Kristoff
Ruy M Ribeiro
Dongzhu Ma
Anita Trichel
Hadega Aamer
Tammy Dunsmore
Jennifer L Stock
Published In
J Virol
PLoS Pathog
PLoS One
J Clin Invest
Affiliations
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Recent Articles
1.
Dynamics of Simian Immunodeficiency Virus Two-Long-Terminal-Repeat Circles in the Presence and Absence of CD8 Cells
Policicchio B, Cardozo E, Sette P, Xu C, Haret-Richter G, Dunsmore T, et al.
J Virol . 2018 Apr; 92(13). PMID: 29643246
CD8 cells play a key role in human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) infection, but their specific mechanism(s) of action in controlling the virus is unclear. Two-long-terminal-repeat (2-LTR) circles...
2.
Emergence of resistance mutations in simian immunodeficiency virus (SIV)-infected rhesus macaques receiving non-suppressive antiretroviral therapy (ART)
Policicchio B, Sette P, Xu C, Haret-Richter G, Dunsmore T, Pandrea I, et al.
PLoS One . 2018 Feb; 13(2):e0190908. PMID: 29466356
Two SIVmac251-infected rhesus macaques received tenofovir/emtricitabine with raltegravir intensification. Viral rebound occurred during treatment and sequencing of reverse transcriptase and integrase genes identified multiple resistance mutations. Similar to HIV infection,...
3.
Simian Immunodeficiency Virus SIVsab Infection of Rhesus Macaques as a Model of Complete Immunological Suppression with Persistent Reservoirs of Replication-Competent Virus: Implications for Cure Research
Ma D, Xu C, Cillo A, Policicchio B, Kristoff J, Haret-Richter G, et al.
J Virol . 2015 Apr; 89(11):6155-60. PMID: 25833043
Simian immunodeficiency virus SIVsab infection is completely controlled in rhesus macaques (RMs) through functional immune responses. We report that in SIVsab-infected RMs, (i) viral replication is controlled to <0 to...
4.
Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication
Kristoff J, Haret-Richter G, Ma D, Ribeiro R, Xu C, Cornell E, et al.
J Clin Invest . 2014 May; 124(6):2802-6. PMID: 24837437
Damage to the intestinal mucosa results in the translocation of microbes from the intestinal lumen into the circulation. Microbial translocation has been proposed to trigger immune activation, inflammation, and coagulopathy,...
5.
Pathogenic features associated with increased virulence upon Simian immunodeficiency virus cross-species transmission from natural hosts
Mandell D, Kristoff J, Gaufin T, Gautam R, Ma D, Sandler N, et al.
J Virol . 2014 Apr; 88(12):6778-92. PMID: 24696477
Unlabelled: While simian immunodeficiency viruses (SIVs) are generally nonpathogenic in their natural hosts, dramatic increases in pathogenicity may occur upon cross-species transmission to new hosts. Deciphering the drivers of these...
6.
Kinetics of myeloid dendritic cell trafficking and activation: impact on progressive, nonprogressive and controlled SIV infections
Wijewardana V, Kristoff J, Xu C, Ma D, Haret-Richter G, Stock J, et al.
PLoS Pathog . 2013 Oct; 9(10):e1003600. PMID: 24098110
We assessed the role of myeloid dendritic cells (mDCs) in the outcome of SIV infection by comparing and contrasting their frequency, mobilization, phenotype, cytokine production and apoptosis in pathogenic (pigtailed...