Geoffrey L Allen
Overview
Explore the profile of Geoffrey L Allen including associated specialties, affiliations and a list of published articles.
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41
Citations
1679
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Recent Articles
1.
Stanski N, Zhang B, Cvijanovich N, Fitzgerald J, Bigham M, Jain P, et al.
Pediatr Crit Care Med
. 2024 Aug;
25(11):1005-1016.
PMID: 39115853
Objectives: We previously derived the updated Pediatric Sepsis Biomarker Risk for Acute Kidney Injury (PERSEVERE-II AKI) prediction model, which had robust diagnostic test characteristics for severe AKI on day 3...
2.
Clark N, Kyler K, Allen G, Ausmus A, Berg K, Beyer J, et al.
Hosp Pediatr
. 2024 Jul;
14(8):642-648.
PMID: 39011551
Background And Objectives: Alarms at hospitals are frequent and can lead to alarm fatigue posing patient safety risks. We aimed to describe alarm burden over a 1-year period and explored...
3.
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Crit Care
. 2023 Jul;
27(1):260.
PMID: 37400882
Background: Sepsis-associated acute kidney injury (SA-AKI) is associated with high morbidity, with no current therapies available beyond continuous renal replacement therapy (CRRT). Systemic inflammation and endothelial dysfunction are key drivers...
4.
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Crit Care
. 2023 Jun;
27(1):250.
PMID: 37365661
Background: Sepsis is associated with significant mortality. Yet, there are no efficacious therapies beyond antibiotics. PCSK9 loss-of-function (LOF) and inhibition, through enhanced low-density lipoprotein receptor (LDLR) mediated endotoxin clearance, holds...
5.
Stanski N, Pode Shakked N, Zhang B, Cvijanovich N, Fitzgerald J, Jain P, et al.
Pediatr Nephrol
. 2023 Mar;
38(9):3099-3108.
PMID: 36939916
Background: Studies in critically ill adults demonstrate associations between serum renin concentrations (a proposed surrogate for renin-angiotensin-aldosterone system dysregulation) and poor outcomes, but data in critically ill children are lacking....
6.
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Res Sq
. 2023 Feb;
PMID: 36778250
Sepsis is associated with significant mortality, yet there are no efficacious therapies beyond antibiotics and supportive care. In adult sepsis studies, PCSK9 loss-of-function (LOF) and inhibition has shown therapeutic promise,...
7.
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Crit Care
. 2022 Jul;
26(1):210.
PMID: 35818064
Background: Multiple organ dysfunction syndrome (MODS) is a critical driver of sepsis morbidity and mortality in children. Early identification of those at risk of death and persistent organ dysfunctions is...
8.
Stanski N, Wong H, Basu R, Cvijanovich N, Fitzgerald J, Weiss S, et al.
Kidney Int Rep
. 2021 Jul;
6(7):1858-1867.
PMID: 34307980
Introduction: Sepsis-associated acute kidney injury (AKI) is a common diagnosis in children that is associated with poor outcomes. The lack of therapeutic options once present makes early identification of at-risk...
9.
Miller-Smith L, Flint J, Allen G
Semin Pediatr Surg
. 2021 May;
30(2):151037.
PMID: 33992314
Cardiac critical care has become an increasingly complex subspecialty, involving multiple subspecialists to support patients with congenital heart disease. This requires understanding of their physiology and the impact of medical...
10.
Atreya M, Whitacre B, Cvijanovich N, Bigham M, Thomas N, Schwarz A, et al.
Crit Care Med
. 2020 Aug;
48(10):1513-1520.
PMID: 32769621
Objectives: Proprotein convertase subtilisin/kexin type 9 is a central regulator of lipid metabolism and has been implicated in regulating the host response to sepsis. Proprotein convertase subtilisin/kexin type 9 loss-of-function...