Geoffrey L Allen
Overview
Explore the profile of Geoffrey L Allen including associated specialties, affiliations and a list of published articles.
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41
Citations
1679
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Recent Articles
11.
PERSEVERE Biomarkers Predict Severe Acute Kidney Injury and Renal Recovery in Pediatric Septic Shock
Stanski N, Stenson E, Cvijanovich N, Weiss S, Fitzgerald J, Bigham M, et al.
Am J Respir Crit Care Med
. 2020 Jan;
201(7):848-855.
PMID: 31916857
Acute kidney injury (AKI), a common complication of sepsis, is associated with substantial morbidity and mortality and lacks definitive disease-modifying therapy. Early, reliable identification of at-risk patients is important for...
12.
Wong H, Caldwell J, Cvijanovich N, Weiss S, Fitzgerald J, Bigham M, et al.
Sci Transl Med
. 2019 Nov;
11(518).
PMID: 31723040
Sepsis remains a major public health problem with no major therapeutic advances over the last several decades. The clinical and biological heterogeneity of sepsis have limited success of potential new...
13.
Stenson E, Cvijanovich N, Allen G, Thomas N, Bigham M, Weiss S, et al.
Intensive Care Med
. 2018 Oct;
44(11):2004-2005.
PMID: 30324289
No abstract available.
14.
Stenson E, Cvijanovich N, Anas N, Allen G, Thomas N, Bigham M, et al.
Pediatr Crit Care Med
. 2018 Feb;
19(2):155-160.
PMID: 29394222
Objective: Hyperchloremia is associated with poor outcome among critically ill adults, but it is unknown if a similar association exists among critically ill children. We determined if hyperchloremia is associated...
15.
Wong H, Cvijanovich N, Anas N, Allen G, Thomas N, Bigham M, et al.
Crit Care Med
. 2017 Dec;
46(3):e242-e249.
PMID: 29252929
Objective: We previously identified septic shock endotypes A and B based on 100 genes reflecting adaptive immunity and glucocorticoid receptor signaling. The endotypes differ with respect to outcome and corticosteroid...
16.
Wong H, Cvijanovich N, Anas N, Allen G, Thomas N, Bigham M, et al.
Am J Respir Crit Care Med
. 2017 Mar;
196(4):494-501.
PMID: 28324661
Rationale: We previously derived and validated the Pediatric Sepsis Biomarker Risk Model (PERSEVERE) to estimate baseline mortality risk in children with septic shock. The PERSEVERE biomarkers are serum proteins selected...
17.
Weiss S, Asaro L, Flori H, Allen G, Wypij D, Curley M
Pediatr Crit Care Med
. 2017 Feb;
18(4):319-329.
PMID: 28212163
Objectives: The impact of extrapulmonary organ dysfunction, independent from sepsis and lung injury severity, on outcomes in pediatric acute respiratory failure is unclear. We sought to determine the frequency, timing,...
18.
Cvijanovich N, Anas N, Allen G, Thomas N, Bigham M, Weiss S, et al.
Pediatr Crit Care Med
. 2017 Feb;
18(4):299-303.
PMID: 28178077
Objective: Polymorphisms of the glucocorticoid receptor gene are associated with outcome and corticosteroid responsiveness among patients with inflammatory disorders. We conducted a candidate gene association study to test the hypothesis...
19.
Wong H, Cvijanovich N, Anas N, Allen G, Thomas N, Bigham M, et al.
Crit Care Med
. 2016 Aug;
44(11):2010-2017.
PMID: 27513537
Objective: The Pediatric Sepsis Biomarker Risk Model (PERSEVERE), a pediatric sepsis risk model, uses biomarkers to estimate baseline mortality risk for pediatric septic shock. It is unknown how PERSEVERE performs...
20.
Wong H, Atkinson S, Cvijanovich N, Anas N, Allen G, Thomas N, et al.
Crit Care Med
. 2016 Jun;
44(10):e1000-3.
PMID: 27270179
Objectives: Prognostic and predictive enrichment strategies are fundamental tools of precision medicine. Identifying children with septic shock who may benefit from corticosteroids remains a challenge. We combined prognostic and predictive...